Mario Ramirez

Publications

• Invasive infections due to Streptococcus pyogenes: seasonal variation of severity and clinical characteristics, Iceland, 1975 to 2012
• Decreasing incidence and changes in serotype distribution of invasive pneumococcal disease in persons aged under 18 years since introduction of 10-valent and 13-valent conjugate vaccines in Portugal, July 2008 to June 2012
• Updated model of group A Streptococcus M proteins based on a comprehensive worldwide study DOI: 10.1111/1469-0691.12134
• The Majority of Adult Pneumococcal Invasive Infections in Portugal Are Still Potentially Vaccine Preventable in Spite of Significant Declines of Serotypes 1 and 5 DOI: 10.1371/journal.pone.0073704
• Superantigen gene complement of Streptococcus pyogenes - Relationship with other typing methods and short-term stability DOI: 10.1007/s10096-012-1726-3
• Serotype discrimination of encapsulated Streptococcus pneumoniae strains by Fourier-transform infrared spectroscopy and chemometrics DOI: 10.1016/j.mimet.2013.02.008
• Scarlet fever is caused by a limited number of streptococcus pyogenes lineages and is associated with the exotoxin genes ssa, speA and speC DOI: 10.1097/INF.0000000000000088
• MiR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells DOI: 10.1186/1756-8722-6-87
• First case of infection with vancomycin-resistant Staphylococcus aureus in Europe DOI: 10.1016/S0140-6736(13)61219-2
• Export of the pneumococcal phage SV1 lysin requires choline-containing teichoic acids and is holin-independent DOI: 10.1111/mmi.12108
• Distribution of pilus islands in Streptococcus agalactiae that cause human infections: Insights into evolution and implication for vaccine development DOI: 10.1128/CVI.00529-12
• Changes in Streptococcus pyogenes causing invasive disease in Portugal: Evidence for superantigen gene loss and acquisition DOI: 10.1016/j.ijmm.2013.07.004
• Bioinformatics in bacterial molecular epidemiology and public health: Databases, tools and the next-generation sequencing revolution
• Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease DOI: 10.1016/j.vaccine.2012.06.062
• Serotype changes in adult invasive pneumococcal infections in Portugal did not reduce the high fraction of potentially vaccine preventable infections DOI: 10.1016/j.vaccine.2011.11.022
• PHYLOViZ: Phylogenetic inference and data visualization for sequence based typing methods DOI: 10.1186/1471-2105-13-87
• Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance DOI: 10.1186/1471-2180-12-280
• Dominance of serotype Ia among group B streptococci causing invasive infections in nonpregnant adults in Portugal DOI: 10.1128/JCM.05488-11
• Differences between macrolide-resistant and -susceptible streptococcus pyogenes: Importance of clonal properties in addition to antibiotic consumption DOI: 10.1128/AAC.01133-12
• An ontology and a REST API for sequence based microbial typing data DOI: 10.1007/978-3-642-28062-7_3
• Group B streptococci causing neonatal infections in barcelona are a stable clonal population: 18-Year surveillance DOI: 10.1128/JCM.00271-11
• Evaluation of Jackknife and Bootstrap for defining confidence intervals for pairwise agreement measures DOI: 10.1371/journal.pone.0019539
• Analysis of invasiveness of pneumococcal serotypes and clones circulating in portugal before widespread use of conjugate vaccines reveals heterogeneous behavior of clones expressing the same serotype DOI: 10.1128/JCM.01763-10
• Adjusted Wallace coefficient as a measure of congruence between typing methods DOI: 10.1128/JCM.00624-11
• The Viriato study: Update on antimicrobial resistance of microbial pathogens responsible for community-acquired respiratory tract infections in Portugal
• Serotypes 1, 7F and 19A became the leading causes of pediatric invasive pneumococcal infections in Portugal after 7 years of heptavalent conjugate vaccine use DOI: 10.1016/j.vaccine.2010.06.008
• Prophage spontaneous activation promotes DNA release enhancing biofilm formation in Streptococcus pneumoniae DOI: 10.1371/journal.pone.0015678
• Population genetics of Streptococcus dysgalactiae subspecies equisimilisreveals widely dispersed clones and extensive recombination DOI: 10.1371/journal.pone.0011741
• Fluoroquinolone resistance in Streptococcus dysgalactiae subsp. equisimilis and evidence for a shared global gene pool with Streptococcus pyogenes DOI: 10.1128/AAC.01377-09
• Expanding the diagnosis of pediatric bacteremic pneumococcal pneumonia from blood cultures to molecular methods: Advantages and caveats DOI: 10.1086/656580
• Evidence for rare capsular switching in Streptococcus agalactiae DOI: 10.1128/JB.01130-09
• Denmark14-230 clone as an increasing cause of pneumococcal infection in Portugal within a background of diverse serotype 19A lineages DOI: 10.1128/JCM.00665-09
• The autolysin LytA contributes to efficient bacteriophage progeny release in Streptococcus pneumoniae DOI: 10.1128/JB.00477-09
• Pherotypes are driving genetic differentiation within Streptococcus pneumoniae DOI: 10.1186/1471-2180-9-191
• Global optimal eBURST analysis of multilocus typing data using a graphic matroid approach DOI: 10.1186/1471-2105-10-152
• The presence of the pilus locus is a clonal property among pneumococcal invasive isolates DOI: 10.1186/1471-2180-8-41
• Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays DOI: 10.1186/1471-2164-9-230
• Identification of immunoreactive extracellular proteins of Streptococcus agalactiae in bovine mastitis DOI: 10.1139/W08-083
• Decrease in macrolide resistance and clonal instability among Streptococcus pyogenes in Portugal DOI: 10.1111/j.1469-0691.2008.02104.x
• Changes in Streptococcus pneumoniae serotypes causing invasive disease with non-universal vaccination coverage of the seven-valent conjugate vaccine DOI: 10.1111/j.1469-0691.2008.02031.x
• Analysis of typing methods for epidemiological surveillance of both methicillin-resistant and methicillin-susceptible Staphylococcus aureus strains DOI: 10.1128/JCM.01684-07
• A confidence interval for the wallace coefficient of concordance and its application to microbial typing methods DOI: 10.1371/journal.pone.0003696
• Streptococcus agalactiae serotype Ib as an agent of meningitis in two adult nonpregnant women DOI: 10.1128/JCM.01358-07
• Reevaluating the serotype II capsular locus of Streptococcus agalactiae DOI: 10.1128/JCM.01296-07
• Ranked adjusted rand: Integrating distance and partition information in a measure of clustering agreement DOI: 10.1186/1471-2105-8-44
• Nonoutbreak surveillance of group A streptococci causing invasive disease in Portugal identified internationally disseminated clones among members of a genetically heterogeneous population DOI: 10.1128/JCM.00496-07
• Analysis of group B streptococcal isolates from infants and pregnant women in Portugal revealing two lineages with enhanced invasiveness DOI: 10.1128/JCM.01182-07
• The Viriato Study: Update of antimicrobial susceptibility data of bacterial pathogens from community-acquired respiratory tract infections in Portugal in 2003 and 2004 | Estudo Viriato: Actualização de dados de susceptibilidade aos antimicrobianos de bactérias responsáveis por infecções adquiridas na comunidade em Portugal em 2003 e 2004
• Illustration of a common framework for relating multiple typing methods by application to macrolide-resistant Streptococcus pyogenes DOI: 10.1128/JCM.02536-05
• Identification of macrolide-resistant clones of Streptoccus pyogenes in Portugal DOI: 10.1111/j.1469-0691.2006.01408.x
• Heterogeneity of pneumococcal phase variants in invasive human infections DOI: 10.1186/1471-2180-6-67
• Emergence of optochin resistance among Streptococcus pneumoniae in Portugal DOI: 10.1089/mdr.2006.12.239
• DNA methylase activity as a marker for the presence of a family of phage-like elements conferring efflux-mediated macrolide resistance in streptococci DOI: 10.1128/AAC.00782-06
• Clonal relationships between invasive and noninvasive Lancefield group C and G Streptococci and emm-specific differences in invasiveness DOI: 10.1128/JCM.44.3.841-846.2006
• Rapid inversion of the prevalences of macrolide resistance phenotypes paralleled by a diversification of T and emm types among Streptococcus pyogenes in Portugal DOI: 10.1128/AAC.49.5.2109-2111.2005
• Characterization of the genetic lineages responsible for pneumococcal invasive disease in Portugal DOI: 10.1128/JCM.43.4.1706-1715.2005
• Streptococcus agalactiae in a Large Portuguese Teaching Hospital: Antimicrobial Susceptibility, Serotype Distribution, and Clonal Analysis of Macrolide-Resistant Isolates DOI: 10.1089/107662904323047772
• Invasive Streptococcus pneumoniae from Portugal: Implications for vaccination and antimicrobial therapy DOI: 10.1111/j.1469-0691.2004.00869.x
• Serotyping Streptococcus pneumoniae by multiplex PCR
• Macrolide resistance in Streptococcus pneumoniae isolated from patients with community-acquired lower respiratory tract infections in Portugal: Results of a 3-year (1999-2001) multicenter surveillance study
• Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin in Spain: Clonal diversity and appearance of ciprofloxacin-resistant epidemic clones DOI: 10.1128/AAC.45.10.2955-2957.2001
• Prophage carriage as a molecular epidemiological marker in Streptococcus pneumoniae
• Acquisition of new capsular genes among clinical isolates of antibiotic- resistant Streptococcus pneumoniae
• A high incidence of prophage carriage among natural isolates of Streptococcus pneumoniae
• Molecular epidemiology of penicillin-resistant Streptococcus pneumoniae isolates recovered in Italy from 1993 to 1996
• Molecular characterization of the complete 23F capsular polysaccharide locus of Streptococcus pneumoniae
• Capsular transformation of a multidrug-resistant Streptococcus pneumoniae in vivo
• Ubiquitous distribution of the competence related genes comA and comC among isolates of Streptococcus pneumoniae
• Evidence for the geographic spread of a methicillin-resistant Staphylococcus aureus clone between Portugal and Spain
• Pherotype Influences Biofilm Growth and Recombination in Streptococcus pneumoniae DOI: 10.1371/journal.pone.0092138
• PCR based differentiation between Streptococcus dysgalactiae subsp equisimilis strains isolated from humans and horses DOI: 10.1016/j.cimid.2014.04.001
• Non-invasive pneumococcal pneumonia in portugal-serotype distribution and antimicrobial resistance. DOI: 10.1371/journal.pone.0103092
• Induction of Prophages by Fluoroquinolones in Streptococcus pneumoniae: Implications for Emergence of Resistance in Genetically-Related Clones DOI: 10.1371/journal.pone.0094358
• Comparison of alternative mixture model methods to analyze bacterial CGH experiments with multi-genome arrays. DOI: 10.1186/1756-0500-7-148