Gary Mirams

Wellcome Trust Senior Research Fellow (Bioinformatics and computational biology not elsewhere classified)

Nottingham, UK

I am a mathematical physiologist working at the University of Nottingham. For more details please see my homepage at


  • A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling
  • Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing
  • Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials
  • Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
  • Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates
  • Is it time for in silico simulation of drug cardiac side effects?
  • High-throughput functional curation of cellular electrophysiology models
  • Functional Curation: Potential Future Directions for SED-ML
  • Novel Approaches to Assessing Cardiac Safety – Proceedings of a Workshop
  • Multiscale Modeling of Colonic Crypts and Early Colorectal Cancer
  • The significant effect of the choice of ionic current integration method in cardiac electro-physiological simulations
  • Modelling Spatially Regulated β-Catenin Dynamics and Invasion in Intestinal Crypts
  • A multiple timescale analysis of a mathematical model of the Wnt/β-catenin signalling pathway
  • Chaste: A test-driven approach to software development for biological modelling
  • A Local Sensitivity Analysis Method for Developing Biological Models with Identifiable Parameters: Application to L-type Calcium Channel Modelling
  • Phenomenological modeling of cell-to-cell and beat-to-beat variability in isolated Guinea Pig ventricular myocytes

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