Gary Mirams

Publications

• A local sensitivity analysis method for developing biological models with identifiable parameters: Application to cardiac ionic channel modelling
• Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing
• Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials
• Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
• Stochasticity in Action Potential duration Enhances Dispersion of Repolarisation at Fast Pacing Rates
• Is it time for in silico simulation of drug cardiac side effects?
• High-throughput functional curation of cellular electrophysiology models
• Functional Curation: Potential Future Directions for SED-ML
• Novel Approaches to Assessing Cardiac Safety – Proceedings of a Workshop
• Multiscale Modeling of Colonic Crypts and Early Colorectal Cancer
• The significant effect of the choice of ionic current integration method in cardiac electro-physiological simulations
• Modelling Spatially Regulated β-Catenin Dynamics and Invasion in Intestinal Crypts
• A multiple timescale analysis of a mathematical model of the Wnt/β-catenin signalling pathway
• Chaste: A test-driven approach to software development for biological modelling
• A Local Sensitivity Analysis Method for Developing Biological Models with Identifiable Parameters: Application to L-type Calcium Channel Modelling
• Phenomenological modeling of cell-to-cell and beat-to-beat variability in isolated Guinea Pig ventricular myocytes