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Retinal Pigment Epithelium (RPE) Pipeline Segmentation and Analysis Software

software
posted on 2025-04-28, 22:48 authored by Davide OrtolanDavide Ortolan, Pushkar Sathe, Andrei Volkov, Dominik Reichert, Sheldon Sebastian, Arvydas Maminishkis, Nicholas Shaub, Bengt Ljungquist, Devika Bose, Jorge Ferrari, Nyusha Lin, Gianluca PegoraroGianluca Pegoraro, Carl Simon, Ruchi Sharma, Peter Bajcsy, Kapil Bharti

This item contains a software developed for Windows systems (RPE_Pipeline-Win64) to segment and analyze retinal pigment epithelium (RPE) cell and nucleus borders and sixteen intracellular organelles and structures. Specific instructions to use the software are available at https://github.com/NIH-NEI/RPE_Pipeline

A small demo dataset (RpeMapDemoData) and training data (RpeMapTrainingData) are also included.

Funding

Developing functional and authenticated RPE tissue from iPS cells

National Eye Institute

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History

Research Institution(s)

National Eye Institute; National Institute of Standards and Technology; National Center for Advancing Translational Sciences; National Cancer Institute

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