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Gianluca Pegoraro

Associate Scientist (Biological sciences)

Bethesda, MD, USA

Publications

  • siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection
  • Ageing-related chromatin defects through loss of the NURD complex
  • Cell cycle staging of individual cells by fluorescence microscopy
  • Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging
  • A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages
  • Identification of Gene Positioning Factors Using High-Throughput Imaging Mapping
  • Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430
  • Crimean-Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway
  • The central role of chromatin maintenance in aging.
  • Regulation of adeno-associated virus DNA replication by the cellular TAF-I/set complex
  • Nuclear organization and the control of HIV-1 transcription
  • Recruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML protein
  • Histone modifications predispose genome regions to breakage and translocation
  • Shedding light on filovirus infection with high-content imaging
  • Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining
  • Integrating High-Content Imaging and Chemical Genetics to Probe Host Cellular Pathways Critical for Yersinia Pestis Infection
  • Identification of mammalian protein quality control factors by high-throughput cellular imaging
  • High-throughput imaging of mRNA at the single-cell level in human primary immune cells
  • Cajal bodies are linked to genome conformation
  • High-throughput Imaging as a versatile and unbiased discovery tool
  • 3D Chromosome Regulatory Landscape of Human Pluripotent Cells
  • CTCF is a Barrier for Totipotent-like Reprogramming
  • The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation
  • HiFENS: High-throughput FISH detection of endogenous pre-mRNA splicing isoforms
  • Activation of endoplasmic reticulum stress via clustering of the inner nuclear membrane protein SUN2
  • HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells
  • Spatiotemporal higher-order chromatin landscape of human histone gene clusters at Histone Locus Bodies during the cell cycle in breast cancer progression
  • Spatiotemporal higher-order chromatin landscape of human histone gene clusters at histone locus bodies during the cell cycle in breast cancer progression
  • Identification of epigenetic modulators as determinants of nuclear size and shape
  • HiTIPS: High-Throughput Image Processing Software for the Study of Nuclear Architecture and Gene Expression
  • Allele-level visualization of transcription and chromatin by high-throughput imaging

Gianluca Pegoraro's public data