This h5ad contains splicing differences in the Tabula Sapiens atlas. For each cell, a splicing score, called the SpliZ, is assigned to each gene with enough informative splicing information (Olivieri et. al. 2021). This object contains both gene expression values (labeled with the gene name, e.g. “MYL6”) and splicing values (labeled with the gene name and “SpliZ”, e.g. “MYL6_SpliZ”). Low SpliZ values correspond to shorter introns on average across the gene, while high SpliZ values correspond to longer introns on average. The splice junctions for each gene in a cell have been called based on the SICILIAN method (Dehghannasiri et. al., 2020).
Funding
This project has been made possible in part by grant number 2019-203354 from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation.