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Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

Version 2 2022-04-01, 13:33
Version 1 2022-03-31, 16:40
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posted on 2022-03-31, 16:40 authored by Rebecca McHugh, John Munnoch, Andrew J Roe, Paul A HoskissonPaul A Hoskisson

We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71 %. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.


These data represent the FastQ outputs from the Oxford Nanopore sequencing that contributed to the hybrid genome assembly.

Funding

Chance and Necessity: Evolution guided antibiotic improvement and discovery

Biotechnology and Biological Sciences Research Council

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Re-engineering robustness in to industrial antibiotic producing Streptomyces strains

Biotechnology and Biological Sciences Research Council

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Royal Academy of Engineering Research Chair (RCSRF2021\11\15)

MR/V011499/1

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