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Implications of low muscle mass across the continuum of care: a narrative review

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Version 2 2018-09-12, 15:18
Version 1 2018-08-31, 20:33
journal contribution
posted on 2018-09-12, 15:18 authored by Carla M. Prado, Sarah A. Purcell, Carolyn Alish, Suzette L. Pereira, Nicolaas E. Deutz, Daren K. Heyland, Bret H. Goodpaster, Kelly A. Tappenden, Steven B. Heymsfield

Abnormalities in body composition can occur at any body weight. Low muscle mass is a predictor of poor morbidity and mortality and occurs in several populations. This narrative review provides an overview of the importance of low muscle mass on health outcomes for patients in inpatient, outpatient and long-term care clinical settings. A one-year glimpse at publications that showcases the rapidly growing research of body composition in clinical settings is included. Low muscle mass is associated with outcomes such as higher surgical and post-operative complications, longer length of hospital stay, lower physical function, poorer quality of life and shorter survival. As such, the potential clinical benefits of preventing and reversing this condition are likely to impact patient outcomes and resource utilization/health care costs. Clinically viable tools to measure body composition are needed for routine screening and intervention. Future research studies should elucidate the effectiveness of multimodal interventions to counteract low muscle mass for optimal patient outcomes across the healthcare continuum.Key messages

Low muscle mass is associated with several negative outcomes across the healthcare continuum.

Techniques to identify and counteract low muscle mass in clinical settings are needed.

Low muscle mass is associated with several negative outcomes across the healthcare continuum.

Techniques to identify and counteract low muscle mass in clinical settings are needed.

Funding

Research reported in this publication was supported by the National Institute of Environmental Health Sciences under grant number P30ES023512 and the National Heart, Lung, and Blood Institute under grant number R01HL132887 of the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Carla M. Prado is supported by a Canadian Institutes of Health Research (CIHR) New Investigator Salary Award and the Campus Alberta Innovates Research Chair Program. Sarah Purcell has received honorarium from Abbott.

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