cs5b01182_si_001.pdf (4.7 MB)
Indole-Catalyzed Bromolactonization in Lipophilic Solvent: A Solid–Liquid Phase Transfer Approach
journal contribution
posted on 2015-08-07, 00:00 authored by Tao Chen, Thomas Jian Yao Foo, Ying-Yeung YeungWe have developed a novel indole-catalyzed
bromolactonization of
olefinic acids. The reaction could be conducted in lipophilic solvent
through a solid–liquid phase transfer mechanism. This catalytic
protocol has been applied to the synthesis of base-sensitive bromolactones.