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An Easily Available Ratiometric Reaction-Based AIE Probe for Carbon Monoxide Light-up Imaging
journal contribution
posted on 2019-07-22, 12:35 authored by Jianguo Wang, Chunbin Li, Qingqing Chen, Hongfeng Li, Lihua Zhou, Xing Jiang, Mengxue Shi, Pengfei Zhang, Guoyu Jiang, Ben Zhong TangCarbon
monoxide (CO) is a significant gasotransmitter that naturally
modulates inflammatory responses. Visualization of CO in situ would help to reveal its physiological/pathological functions. Unfortunately,
most existing CO fluorescent probes show aggregation-caused quenching
(ACQ) properties. Herein, we report the reaction-based fluorescent
probe (BTCV-CO) with aggregation-induced emission (AIE) characteristics
for CO detection and imaging. This ratiometric AIE probe showed excellent
stability, high sensitivity (detection limit of 30.8 nM), and superior
selectivity. More importantly, this CO-responsive AIE probe could
be facilely designed and easily obtained by two-step synthesis with
high yield, providing an easy-to-handle AIE toolbox for real-time
visualization of CO in a living system.