Figure 5

Fig. 5. Increased VAChT expression ameliorates amyloid pathology in App^NL-F males but not in females. (C) Immunoblot of VAChT expression in the cortex of AAV-VAChT-injected App^NL-F males at 12 months of age compared to AAV-mCherry-injected controls. Synaptophysin (syn) was used as loading control. (E) Immunoblot of VAChT expression in the cortex of AAV-VAChT-injected App^NL-F females at 12 months of age compared to AAV-mCherry-injected controls. Synaptophysin (syn) was used as loading control.