TCR beta repertoires in naive CD4+ T cell subsets in identical twin donor samples
TCR repertoire datasets for sorted naive CD4+ T cell subsets.
Includes metadata and preprocessed clonesets for sorted naive CD4+ T cell subsets: naive Treg, CD31+-enriched (recent thymic emigrates, RTE subset), CD31- naive subset (non-RTE subset, mature naive CD4+ T cells).
Naive T cell subsets were sorted from 5 pairs of identical twins, all 28-35 years old males; and two more healthy donors (not twins).
Each sample is presented in txt file: TCR beta cloneset tab-delimited table, VDJtools software format.
Raw sequencing fastq data was processed with using MIGEC v.1.2.9 (threshold 1 UMI for CDR3-containing clonotype), aligned with MiXCR v.2.1.1. In-frame TCR CDR3 repertoires were extracted with VDJtools v. 1.2.1.