figshare
Browse
TEXT
A1_mNaive_TRB.txt (3.34 MB)
TEXT
A1_nTreg_TRB.txt (4.74 MB)
TEXT
A1_RTE_TRB.txt (2.13 MB)
TEXT
A2_mNaive_TRB.txt (6.73 MB)
TEXT
A2_nTreg_TRB.txt (7.43 MB)
TEXT
A2_RTE_TRB.txt (4.53 MB)
TEXT
B1_mNaive_TRB.txt (5.48 MB)
TEXT
B1_nTreg_TRB.txt (3.97 MB)
TEXT
B1_RTE_TRB.txt (5.59 MB)
TEXT
B2_mNaive_TRB.txt (8.61 MB)
TEXT
B2_nTreg_TRB.txt (4.79 MB)
TEXT
B2_RTE_TRB.txt (4.54 MB)
TEXT
C1_mNaive_TRB.txt (4.85 MB)
TEXT
C1_nTreg_TRB.txt (3.12 MB)
TEXT
C1_RTE_TRB.txt (5.95 MB)
TEXT
C2_mNaive_TRB.txt (4.59 MB)
TEXT
C2_nTreg_TRB.txt (4.03 MB)
TEXT
C2_RTE_TRB.txt (5.52 MB)
TEXT
E1_mNaive_TRB.txt (4.29 MB)
TEXT
E1_nTreg_TRB.txt (3.76 MB)
1/0
37 files

TCR beta repertoires in naive CD4+ T cell subsets in identical twin donor samples

Download all (184.38 MB) This item is shared privately
dataset
modified on 2020-01-30, 11:31

TCR repertoire datasets for sorted naive CD4+ T cell subsets.


Includes metadata and preprocessed clonesets for sorted naive CD4+ T cell subsets: naive Treg, CD31+-enriched (recent thymic emigrates, RTE subset), CD31- naive subset (non-RTE subset, mature naive CD4+ T cells).

Naive T cell subsets were sorted from 5 pairs of identical twins, all 28-35 years old males; and two more healthy donors (not twins).

Each sample is presented in txt file: TCR beta cloneset tab-delimited table, VDJtools software format.


Raw sequencing fastq data was processed with using MIGEC v.1.2.9 (threshold 1 UMI for CDR3-containing clonotype), aligned with MiXCR v.2.1.1. In-frame TCR CDR3 repertoires were extracted with VDJtools v. 1.2.1.

Funding

Ministry of Science and Higher Education of the Russian Federation grant (075-15-2019-1789)