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Low-grade neuroepithelial tumors with FGFR2 fusion

Published on by David Solomon
Representative scanned pathology slides from 9 patients with low-grade neuroepithelial tumors harboring FGFR2 gene fusions and epigenetically aligning with polymorphous low-grade neuroepithelial tumor of the young (PLNTY). Included are hematoxylin and eosin stained sections and CD34 immunohistochemical stains from the 9 cases. These were scanned on an Aperio digital slide scanner, and the .SVS files can be viewed using the freely downloadable ImageScope software from Leica Biosystems. The complete clinical, histopathologic, genetic, and epigenomic features of these 9 cases are described in detail in the following report: Gupta R, et al. Low-grade glioneuronal tumors with FGFR2 fusion resolve into a single epigenetic group corresponding to 'Polymorphous low-grade neuroepithelial tumor of the young'. Acta Neuropathologica 2021 Epub July 28, PMID: 34322742

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Funding

National Institutes of Health, NIH Director's Early Independence Award (DP5 OD021403)

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