Loss of Endothelial HIF-Prolyl hydroxylase 2 (PHD2) Induces Cardiac Hypertrophy and Fibrosis

Published on by Zhiyu Dai
Cardiac hypertrophy is a common adaptive response to injury and stress, and can eventually lead to heart failure. In this study, we investigated the role of endothelial Prolyl-4 hydroxylase 2 (PHD2)/hypoxia inducible factors (HIFs) signaling in the pathogenesis of heart failure.

Cite items from this project

cite all items

Funding

Novel mechanisms of obliterative pulmonary vascular remodeling and sever pulmonary arterial hypertensionNational Heart Lung and Blood InstituteFind out more...

Targeting Smooth Muscle Progenitor Cells for Treatment of Pulmonary Arterial HypertensionNational Heart Lung and Blood InstituteFind out more...

Novel Signalings and Molecular Targets Of Endothelial Regeneration In Aging LungNational Heart Lung and Blood InstituteFind out more...

R01HL148810

Role of Smooth Muscle Progenitor Cells in Obliterative Vascular Remodeling and PHNational Heart Lung and Blood InstituteFind out more...

20CDA35310084

ATS Foundation and Pulmonary Hypertension Association Research Fellowship

Share

email