De novo replication repair deficient glioblastoma, IDH-wildtype
Representative scanned pathology slides from "De novo replication repair deficient glioblastoma, IDH-wildtype" occurring in the cerebral hemispheres in adults. Included are hematoxylin and eosin stained sections and representative immunohistochemical stains. These were scanned on an Aperio digital slide scanner, and the .SVS files can be viewed using the freely downloadable ImageScope software from Leica Biosystems. The complete clinical, histopathologic, genetic, and epigenomic features of these de novo replication repair deficient glioblastoma, IDH-wildtype are described in detail in the following report: Hadad S and Gupta R, et al. "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade. Acta Neuropathologica 147: 3, 2024. PMID: 38079020