Visualizing the vasculature of the entire human eye posterior hemisphere without contrast agent

Ferguson, R. Daniel

Visualizing the vasculature of the entire human eye posterior hemisphere without contrast agent

Posted on 2018-12-12 - 16:24

The platform described here combines non-invasive measurement of retina/choroid structure and ocular blood flow based on Optical Coherence Tomography (OCT) and wide-field semi-quantitative global flow visualization using Line-scanning Doppler Flowmetry (LSDF). The combination of these two imaging modalities within the same platform enables comprehensive assessment of blood flow in the retina and choroid in animals and human subjects with normal vision or with various retinal diseases. Ultra-widefield vasculature visualization is demonstrated here for the first time without injecting additional contrast agents and based only on the motion of particles within the vasculature.

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Mujat, Mircea; Lu, Yang; Maguluri, Gopi; Zhao, Youbo; Iftimia, Nicusor; Ferguson, R. Daniel (2018). Visualizing the vasculature of the entire human eye posterior hemisphere without contrast agent. Optica Publishing Group. Collection. https://doi.org/10.6084/m9.figshare.c.4241498.v1

https://doi.org/10.6084/m9.figshare.c.4241498.v1

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