Transfer Hydrogenation
of Aldehydes, Allylic Alcohols, Ketones, and Imines Using Molybdenum
Cyclopentadienone Complexes
Posted on 2018-04-16 - 12:48
The
molybdenum tetraphenylcyclopentadienone complex (C5Ph4O)Mo(CO)3(CH3CN) 1a is an effective precatalyst for the transfer
hydrogenation of aldehydes, allylic alcohols, ketones, and imines
under mild conditions with either 2-propanol or formic acid as reducing
reagent. Mechanistic studies suggest that these molybdenum cyclopentadienone
complexes can be reduced to the corresponding hydroxycyclopentadienyl
Mo hydrides. These complexes, by virtue of the hydroxyl group on the
cyclopentadienyl ligand, are more reactive and chemoselective than
the analogous cyclopentadienyl molybdenum complexes for the reduction
of ketones, aldehydes, and imines.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Wu, Weiwei; Seki, Tomohiro; Walker, Katherine L.; Waymouth, Robert M. (2018). Transfer Hydrogenation
of Aldehydes, Allylic Alcohols, Ketones, and Imines Using Molybdenum
Cyclopentadienone Complexes. ACS Publications. Collection. https://doi.org/10.1021/acs.organomet.8b00086
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (4)
WW
Weiwei Wu
TS
Tomohiro Seki
KW
Katherine L. Walker
RW
Robert M. Waymouth
KEYWORDS
formic acid2- propanolcyclopentadienyl molybdenum complexesTransfer HydrogenationiminealdehydeAllylic Alcoholsmolybdenum cyclopentadienone complexesCHCNMechanistic studiesallylic alcoholscyclopentadienyl ligandmolybdenum tetraphenylcyclopentadienoneMolybdenum Cyclopentadienone Complexeshydroxyl grouptransfer hydrogenationketonehydroxycyclopentadienyl Mo hydrides