Real-time, label-free, qualitative, intraoperative visualization of peripheral nerves and micro-vasculatures using multimodal optical imaging techniques
Posted on 2018-02-12 - 16:53
Accurate, real-time identification and display of critical anatomic structures, such as nerve and vasculature, are critical for reducing complications and improving surgical outcomes. Human vision is frequently limited in clearly distinguishing and contrasting these structures. We present a novel imaging system, which enables noninvasive visualization of critical anatomic structures during surgical dissection. Peripheral nerves are visualized by a snapshot polarimetry that calculates the anisotropic optical properties. Vascular structures, both venous and arterial, are identified and monitored in real-time using a near-infrared laser-speckle-contrast imaging. We evaluate the system by performing in vivo animal studies with qualitative comparison by contrast-agent-aided fluorescence imaging.
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Cha, Jaepyeong; Broch, Aline; Mudge, Scott; Kim, Kihoon; Namgoong, Jung-Man; Oh, Eugene; et al. (2018). Real-time, label-free, qualitative, intraoperative visualization of peripheral nerves and micro-vasculatures using multimodal optical imaging techniques. Optica Publishing Group. Collection. https://doi.org/10.6084/m9.figshare.c.3945865.v1
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AUTHORS (7)
JC
Jaepyeong Cha
AB
Aline Broch
SM
Scott Mudge
KK
Kihoon Kim
JN
Jung-Man Namgoong
EO
Eugene Oh
PK
Peter Kim