Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark
Posted on 2017-09-07 - 05:00
Abstract Objective Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status. 234 women, recruited from Danish HIV centres as part of a larger observational study on aspects of living with HIV as a woman (the SHADE study), were included. Results We tested cervical samples for M. genitalium by specific PCR. We found three samples positive (1.3%). The women were between 30 and 50 years old, all were of Asian origin, sexually active, and on antiretroviral treatment with supressed HIV RNA and CD4 count >350 cells/µL. None reported symptoms from the lower abdomen. The prevalence of M. genitalium infection in WLWH in Denmark is low, thus systematic screening for M. genitalium in this group does not seem relevant.
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Madsen, Anne; Thorsteinsson, Kristina; Lebech, Anne-Mette; Storgaard, Merete; Katzenstein, Terese; Rönsholt, Frederikke; et al. (2017). Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.3874465.v1
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AUTHORS (11)
AM
Anne Madsen
KT
Kristina Thorsteinsson
AL
Anne-Mette Lebech
MS
Merete Storgaard
TK
Terese Katzenstein
FR
Frederikke Rönsholt
IJ
Isik Johansen
GP
Gitte Pedersen
LN
Lars Nielsen
AA
Aase Andersen
JJ
Jørgen Jensen