Pd-Catalyzed, ortho C–H Methylation
and Fluorination of Benzaldehydes Using Orthanilic Acids as Transient
Directing Groups
Version 3 2018-02-13, 11:13
Version 2 2018-02-12, 22:35
Version 1 2018-02-09, 17:04
Posted on 2018-02-13 - 11:13
The
direct, Pd-catalyzed ortho C–H methylation
and fluorination of benzaldehydes have been accomplished using commercially
available orthanilic acids as transient directing groups. In these
reactions, the 1-fluoro-2,4,6-trimethylpyridinium salts can be either
a bystanding F+ oxidant or an electrophilic fluorinating
reagent. An X-ray crystal structure of a benzaldehyde ortho C–H palladation intermediate was obtained using triphenylphosphine
as the stabilizing ligand.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Chen, Xiao-Yang; Sorensen, Erik J. (2018). Pd-Catalyzed, ortho C–H Methylation
and Fluorination of Benzaldehydes Using Orthanilic Acids as Transient
Directing Groups. ACS Publications. Collection. https://doi.org/10.1021/jacs.8b00048
or
Select your citation style and then place your mouse over the citation text to select it.