Particulate-Aggregated
Adhesives with
Exudate-Sensitive Properties and Sustained Bacteria Disinfection to
Facilitate Wound Healing
Posted on 2020-07-02 - 11:03
Wound-associated infections create
additional suffering and come at a high cost for patients and their
families, which urgently require wound disinfection biomaterials with
improved healing efficacy. Here, we report an adhesive with sustained
bacteria disinfection ability, which is aggregated from hydrogen-bonded
polymer particulates. The particulate-aggregated adhesive shows strong
binding ability on different surfaces from rigid substrates to soft
skins. Moreover, water-sensitive mechanical properties are shown in
wound exudates, resulting from the dissociation of hydrogen bonds
under the competition of water and thus the sustained release of particulates.
Synergizing with the strong binding ability, exudate-sensitive behaviors,
and sustained release of antibacterial particulates, the adhesive
achieves sustained bactericidal activity and can facilitate the healing
process in bacteria-infected skin wounds.
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Hou, Changshun; He, Wenqing; Wang, Zhaoyue; Yi, Bo; Hu, Zuojun; Wang, Wei; et al. (2020). Particulate-Aggregated
Adhesives with
Exudate-Sensitive Properties and Sustained Bacteria Disinfection to
Facilitate Wound Healing. ACS Publications. Collection. https://doi.org/10.1021/acsami.0c04920
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AUTHORS (8)
CH
Changshun Hou
WH
Wenqing He
ZW
Zhaoyue Wang
BY
Bo Yi
ZH
Zuojun Hu
WW
Wei Wang
XD
Xin Deng
XY
Xi Yao