More diversity in epithelial cell polarity: A fruit flies’ gut feeling

Published on 2018-12-05T19:08:50Z (GMT) by
<div><p>Multicellular animals face the principle challenge to deal with two distinct compartments: the internal organismal compartment and the external environment. This challenge is met by the differentiation of cell sheets into epithelia, which provide a dynamic barrier in tissues, organs, and organisms. Cell polarity is key to all functions of epithelia, and compromising polarity causes many severe diseases. Within the past 20 years, research on <i>Drosophila melanogaster</i> discovered a conserved molecular machinery that controls epithelial polarity. Recent findings suggest that the textbook <i>Drosophila</i>-based paradigm of the control of epithelial polarity may not be as universal as previously assumed.</p></div>

Cite this collection

Müller, H-Arno J. (2018): More diversity in epithelial cell polarity: A fruit flies’ gut feeling. PLOS Biology. Collection.