Mechanics
of Mineralized Collagen Fibrils
upon Transient Loads
Posted on 2020-07-07 - 21:29
Collagen
is a key structural protein in the human body, which undergoes mineralization
during the formation of hard tissues. Earlier studies have described
the mechanical behavior of bone at different scales, highlighting
material features across hierarchical structures. Here we present
a study that aims to understand the mechanical properties of mineralized
collagen fibrils upon tensile/compressive transient loads, investigating
how the kinetic energy propagates and it is dissipated at the molecular
scale, thus filling a gap of knowledge in this area. These specific
features are the mechanisms that nature has developed to passively
dissipate stress and prevent structural failures. In addition to the
mechanical properties of the mineralized fibrils, we observe distinct
nanomechanical behaviors for the two regions (i.e., overlap and gap) of the D-period to
highlight the effect of the mineralization. We notice decreasing trends
for both wave speeds and Young’s moduli over input velocity
with a marked strengthening effect in the gap region due to the accumulation
of the hydroxyapatite. In contrast, the dissipative behavior is not
affected by either loading conditions or the mineral percentage, showing
a stronger damping effect upon faster inputs compatible to the bone
behavior at the macroscale. Our results offer insights into the dissipative
behavior of mineralized collagen composites to design and characterize
bioinspired composites for replacement devices (e.g., prostheses for sound transmission or conduction) or optimized structures
able to bear transient loads, for example, impact, fatigue, in structural
applications.
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Milazzo, Mario; Jung, Gang Seob; Danti, Serena; Buehler, Markus J. (2020). Mechanics
of Mineralized Collagen Fibrils
upon Transient Loads. ACS Publications. Collection. https://doi.org/10.1021/acsnano.0c02180
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AUTHORS (4)
MM
Mario Milazzo
GJ
Gang Seob Jung
SD
Serena Danti
MB
Markus J. Buehler