Design and characterization of a combined OCT and wide field imaging falloposcope for ovarian cancer detection
Posted on 2017-04-26 - 17:42
Early detection of ovarian cancer is only achieved in around 20% of women due to lack of effective screening. We propose a method for surveillance of high risk women based on a microendoscope introduced transvaginally to image the fallopian tubes and ovaries. This requires extreme miniaturization of the optics and catheter sheath. We describe the design of a falloposcope that combines optical coherence tomography (OCT) and wide field imaging into a sub-1 mm diameter package. We characterize the systems and show that they provide contrast on ex-vivo samples of ovary and fallopian tube. In addition, we show the mechanical performance of the endoscope in an anatomically correct model of the female reproductive tract.
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Keenan, Molly; Tate, Tyler H.; Kieu, Khanh; Black, John F.; Utzinger, Urs; K. Barton, Jennifer (2017). Design and characterization of a combined OCT and wide field imaging falloposcope for ovarian cancer detection. Optica Publishing Group. Collection. https://doi.org/10.6084/m9.figshare.c.3753449.v1
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Tyler H. Tate
John F. Black
Jennifer K. Barton
ex-vivo samplesimagelackcatheter sheathmicroendoscopeminiaturizationOCTsubcancer detectioncharacterizationsurveillancescreeningendoscopeperformancemethodcontrastfield imagingfallopian tubesopticcoherence tomographytractfield imaging falloposcopemodelmm diameter packagetransvaginallyfallopian tubeovarierisk womenovary