Cost-effectiveness analysis of a communication-focused therapy for pre-school children with autism: results from a randomised controlled trial

Posted on 21.12.2015 - 05:00
Abstract Background Autism is associated with impairments that have life-time consequences for diagnosed individuals and a substantial impact on families. There is growing interest in early interventions for children with autism, yet despite the substantial economic burden, there is little evidence of the cost-effectiveness of such interventions with which to support resource allocation decisions. This study reports an economic evaluation of a parent-mediated, communication-focused therapy carried out within the Pre-School Autism Communication Trial (PACT). Methods 152 pre-school children with autism were randomly assigned to treatment as usual (TAU) or PACT + TAU. Primary outcome was severity of autism symptoms at 13-month follow-up. Economic data included health, education and social services, childcare, parental productivity losses and informal care. Results Clinically meaningful symptom improvement was evident for 53 % of PACT + TAU versus 41 % of TAU (odds ratio 1.91, p = 0.074). Service costs were significantly higher for PACT + TAU (mean difference £4,489, p < 0.001), but the difference in societal costs was smaller and non-significant (mean difference £1,385, p = 0.788) due to lower informal care rates for PACT + TAU. Conclusions Improvements in outcome generated by PACT come at a cost. Although this cost is lower when burden on parents is included, the cost and effectiveness results presented do not support the cost-effectiveness of PACT + TAU compared to TAU alone. Trial registration Current Controlled Trials ISRCTN58133827

CITE THIS COLLECTION

Select your citation style and then place your mouse over the citation text to select it.
Byford, Sarah; Cary, Maria; Barrett, Barbara; Aldred, Catherine; Charman, Tony; Howlin, Patricia; et al. (2016): Cost-effectiveness analysis of a communication-focused therapy for pre-school children with autism: results from a randomised controlled trial. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.3597632.v1
or

SHARE

email

Usage metrics

BMC Psychiatry

AUTHORS (14)

Sarah Byford
Maria Cary
Barbara Barrett
Catherine Aldred
Tony Charman
Patricia Howlin
Kristelle Hudry
Kathy Leadbitter
Ann Le Couteur
Helen McConachie
Andrew Pickles
Vicky Slonims
Kathryn Temple
Jonathan Green
need help?