Cleavage of Hg–C Bonds of Organomercurials
Induced by ImOHSe via Two Distinct Pathways
Posted on 2017-10-12 - 19:33
We show that the N-methylimidazole-based selone ImOHSe having
an N–CH2CH2OH substituent has the remarkable
ability to degrade methylmercury by two distinct pathways. Under basic
conditions, ImOHSe converts MeHgCl into biologically inert
HgSe nanoparticles and Me2Hg via the formation of an unstable
intermediate (MeHg)2Se (pathway I). However, under neutral
conditions, in the absence of any base, ImOHSe facilitates
the cleavage of the Hg–C bond of MeHgCl at room temperature
(23 °C), leading to the formation of a stable cleaved product,
the tetracoordinated mononuclear mercury compound (ImOHSe)2HgCl2 and Me2Hg (pathway II).
The initial rate of Hg–C bond cleavage of MeHgCl induced by
ImOHSe is almost 2-fold higher than the initial rate observed
by ImMeSe. Moreover, we show that ImYSe (Y =
OH, Me) has an excellent ability to dealkylate Me2Hg at
room temperature. Under acidic conditions, in the presence of excess
ImYSe, the volatile and toxic Me2Hg further
decomposes to the tetracoordinated mononuclear mercury compound [(ImYSe)4Hg]2+. In addition, the treatment
of ImOHSe with MeHgCys or MeHgSG in phosphate buffer (pH
8.5) afforded water-soluble Hg(SeS) nanoparticles via unusual ligand
exchange reactions, whereas its derivative ImOMeSe or ImMeSe, lacking the N–CH2CH2OH substituent,
failed to produce Hg(SeS) nanoparticles under identical reaction conditions.
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Banerjee, Mainak; Roy, Gouriprasanna (2017). Cleavage of Hg–C Bonds of Organomercurials
Induced by ImOHSe via Two Distinct Pathways. ACS Publications. Collection. https://doi.org/10.1021/acs.inorgchem.7b01301
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