A Simple Approach to Sensor Discovery and Fabrication on
Self-Assembled Monolayers on Glass
Posted on 2004-06-16 - 00:00
Self-assembled monolayers (SAMs) on glass were used as a platform to sequentially deposit
fluorophores and small molecules for ion sensing. The preorganization provided by the surface avoids the
need for complex receptor design, allowing for a combinatorial approach to sensing systems based on
small molecules. The resulting libraries are easily measured and show varied responses to a series of
both cations and anions. This technology is transferable from the macro- to the microscale both via
microcontact printing (μCP), where the fluorophore is printed onto a glass surface, and via direct attachment
of the fluorophore to microchannel walls. The ease of miniaturization of this technology may make the
generation of a wide variety of simple yet efficient microarrays possible.
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Basabe-Desmonts, Lourdes; Beld, Joris; Zimmerman, Rebecca S.; Hernando, Jordi; Mela, Petra; García Parajó, María F.; et al. (2016). A Simple Approach to Sensor Discovery and Fabrication on
Self-Assembled Monolayers on Glass. ACS Publications. Collection. https://doi.org/10.1021/ja049901o
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AUTHORS (10)
LB
Lourdes Basabe-Desmonts
JB
Joris Beld
RZ
Rebecca S. Zimmerman
JH
Jordi Hernando
PM
Petra Mela
MG
María F. García Parajó
NF
Niek F. van Hulst
Av
Albert van den Berg
DR
David N. Reinhoudt
MC
Mercedes Crego-Calama