A Phosphorescent Rhenium(I) Tricarbonyl Polypyridine Complex Appended with a Fructose Pendant That Exhibits Photocytotoxicity and Enhanced Uptake by Breast Cancer Cells

Published on 2018-07-11T20:45:19Z (GMT) by
We demonstrated that the cytotoxicity of a phosphorescent rhenium­(I) polypyridine complex with a fructose pendant was enhanced upon irradiation and the cellular uptake of the complex was mediated by fructose transporters and inhibited by unmodified fructose but was independent of glucose-specific transporters. This complex has been used to image breast cancer cells, where fructose transporters are overexpressed.

Cite this collection

Zhang, Kenneth Yin; Tso, Karson Ka-Shun; Louie, Man-Wai; Liu, Hua-Wei; Lo, Kenneth Kam-Wing (2018): A Phosphorescent Rhenium(I) Tricarbonyl Polypyridine

Complex Appended with a Fructose Pendant That Exhibits Photocytotoxicity

and Enhanced Uptake by Breast Cancer Cells. ACS Publications. Collection.