A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway
Posted on 2018-10-11 - 12:24
A constitutive activation of the Wnt/β-catenin pathway is an initiating event in colon carcinogenesis. We developed colon cancer cells models that highlight the non-selectivity of previously described inhibitors of the Wnt pathway and we propose our model as a suitable screening system for inhibitors of the pathway.
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Grimaldi, Marina; Boulahtouf, Abdelhay; Prévostel, Corinne; Thierry, Alain; Balaguer, Patrick; Blache, Philippe (2018). A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway. Frontiers. Collection. https://doi.org/10.3389/fphar.2018.01160
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AUTHORS (6)
MG
Marina Grimaldi
AB
Abdelhay Boulahtouf
CP
Corinne Prévostel
AT
Alain Thierry
PB
Patrick Balaguer
PB
Philippe Blache