Dr. Morrison is a mechanical engineer who studied Cardiovascular Biomechanics for two years as a post-doctoral fellow at Stanford University. During that time, she investigated the in vivo biomechanics of the aorta using gated CT imaging; those data are now used as boundary condition inputs for computational modeling and bench-testing of endovascular devices. Her research efforts continue at the Center for Devices and Radiological Health (CDRH). Currently she is the chief Advisor of Computational Modeling for the Office of Device Evaluation, and is leading the Regulatory Review of Computational Modeling working group at CDRH. She dedicates much of her energy towards advancing regulatory science through modeling and simulation because she believes the future of medical device design and evaluation, and thus enhanced patient care, lies with computation and enhanced visualization. Moreover, she is a co-chair of the ASME V&V40 Subcommittee on Computational Modeling of Medical Devices, where she is helping to lead the develop of a strategy to assess the credibility of computational models. She is working with a team at CDRH to implement this strategy into the review of premarket submissions that leverage computational modeling. Additionally, she has been a scientific reviewer on a variety of medical device premarket applications (peripheral implants), principal investigator on two projects, and a technical expert on another since 2008. She is a co-principal investigator on a Critical Path Initiative (CPI) project titled "Leveraging the Simulation-Based Engineering and Medical Imaging Technology Revolutions for Cardiovascular Devices", where she is greatly involved in an effort to enhance the use of simulation-based engineering and computational modeling in the evaluation of medical devices. Also, she is the principal investigator on a CPI project titled “Characterization of Human Aortic Anatomy Project (CHAP)”, a multicenter study examining the biomechanical environment of diseased aortas, where aspects of this research are being funded by FDA’s Office of Women’s Health to investigate disparities in treatment outcomes between men and women for endovascular repair. Finally, she provides technical expertise regarding finite element analysis and medical imaging for a project titled “Assessment of plaque composition, dynamic biomechanics, and therapeutic outcomes in subjects implanted with endovascular devices (ASPECT)”. She received her PhD in Theoretical and Applied Mechanics from Cornell University in 2006.
- Morrison, T.M., Meyer, C.A., Fillinger, M.F., et al., ‘Eligibility for endovascular repair of short neck abdominal aortic aneurysms’, submitted for publication in J of Vasc Surg 2014
- Morrison, T.M., Fillinger, M.F., Fairman, R., Yan, X., et al., ‘Gender differences in AAA anatomy and gender disparities in treatment options’, submitted for publication in J of Vasc Surg 2014
- Ansari, F., Pack, L.K., Brooks, S.B., and Morrison, T.M.*, ‘Design considerations for studies of the biomechanical environment of the femoropopliteal arteries’, J of Vasc Surg 58(3):804-13, 2013
- Sweet, M.P, Fillinger, M.F., Morrison, T.M., and Abel, D.B., ‘The influence of gender and aortic aneurysm size on eligibility for endovascular abdominal aortic aneurysm repair’, J of Vasc Surg 54(4): 931-937, 2011
- Erdemir, A., Guess, T.M., Halloran, J., Tadepalli, S.C., and Morrison, T.M., ‘Considerations for reporting finite element analysis studies in biomechanics’ J of Biomechanics 23;45(4):625-33, 2012
- Morrison, T. M., Choi, G., Zarins, C. K., and Taylor, C.A., “Circumferential and longitudinal cyclic strain of the human thoracic aorta: Age-related changes”, J of Vasc Surg 49(4): 1029-1036, 2009