Shaohe Wang

Publications

• Basement Membrane Regulates Fibronectin Organization Using Sliding Focal Adhesions Driven by a Contractile Winch
• Extracellular matrix dynamics in cell migration, invasion and tissue morphogenesis
• A semi-high-throughput imaging method and data visualization toolkit to analyze C. elegans embryonic development
• Single Molecule RNA FISH (smFISH) in Whole-Mount Mouse Embryonic Organs.
• A High-Resolution C. elegans Essential Gene Network Based on Phenotypic Profiling of a Complex Tissue
• The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules.
• The Microtubule Minus-End-Binding Protein Patronin/PTRN-1 Is Required for Axon Regeneration in C. elegans
• Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos.
• NOCA-1 functions with $γ$-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans
• Patterned cell and matrix dynamics in branching morphogenesis
• A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions
• Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation.
• Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans
• A toolkit for GFP-mediated tissue-specific protein degradation in C. elegans
• CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia
• Localized Lysosome Exocytosis Helps Breach Tissue Barriers
• A high-content imaging approach to profile C. elegans embryonic development.
• The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis.
• Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome.
• Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.
• ZCCHC8 is required for the degradation of pervasive transcripts originating from multiple genomic regulatory features
• Tissue Morphogenesis Through Dynamic Cell and Matrix Interactions.
• CRISPR/Cas9-Mediated Gene Knockout in Cells and Tissues Using Lentivirus.