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Rachel Mcmullan

0000-0003-2677-8016

Wellcome Trust Career Development Fellow (Biochemistry and cell biology not elsewhere classified)

Imperial College London

I completed my undergraduate degree and PhD in Biosciences at The University of Birmingham. Following a postdoc with Stephen Nurrish at the MRC Laboratory for Molecular Cell Biology I moved to Imperial College London as a Wellcome Trust Career Development Fellow in 2010. Research in my lab uses the nematode worm Caenorhabditis elegans as a genetic model organism to dissect how animals respond to infection.

Publications

  • Serotonergic Chemosensory Neurons Modify the C. elegans Immune Response by Regulating G-Protein Signaling in Epithelial Cells. DOI: 10.1371/journal.ppat.1003787
  • G-proteins: Fighting infection on two fronts. DOI: 10.4161/worm.20466
  • Behavioral and immune responses to infection require Gαq- RhoA signaling in C. elegans. DOI: 10.1371/journal.ppat.1002530
  • The Pseudomonas aeruginosa reference strain PA14 displays increased virulence due to a mutation in ladS. DOI: 10.1371/journal.pone.0029113
  • The RHO-1 RhoGTPase modulates fertility and multiple behaviors in adult C. elegans. DOI: 10.1371/journal.pone.0017265
  • Rho deep in thought. DOI: 10.1101/gad.1615807
  • The Galpha12-RGS RhoGEF-RhoA signalling pathway regulates neurotransmitter release in C. elegans. DOI: 10.1038/sj.emboj.7601458
  • Rho is a presynaptic activator of neurotransmitter release at pre-existing synapses in C. elegans. DOI: 10.1101/gad.359706
  • Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. DOI: 10.1016/j.cub.2003.11.050

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Co-workers & collaborators

Alexandra Anderson

Alexandra Anderson

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