Marco Herrera-Valdez

Researcher in Applied Mathematics
Mexico City
My interests center around complex adaptive systems, especially in physiology. My current research seeks to better understand mechanisms underlying nonlinear phenomena spanning different levels of physiological organization, not necessarily different spatiotemporal scales. I combine experimental and theoretical approaches that include dynamical systems, graph theory, computational simulations. For instance, I am studying biophysical principles underlying the formation and reactivation of neural traces within microcircuits. At a macroscopic level, neuronal activity depends on the anatomical connectivity, synaptic plasticity, and the level of heterogeneity in the physiological function of the neurons under consideration. Both of these factors are adaptively changed by neuromodulation, regulation of gene expression, as well as internal and external stimuli. The goal is to understand general principles underlying the changes and the adaptability of functionally connected networks.

Publications

  • Relating ion channel expression, bifurcation structure, and diverse firing patterns in a model of an identified motor neuron DOI: 10.1007/s10827-012-0416-6
  • Membranes with the same ion channel populations but different excitabilities
  • Ensemble response in mushroom body output neurons of the honey bee outpaces spatiotemporal odor processing two synapses earlier in the antennal lobe
  • Reduced models for the pacemaker dynamics of cardiac cells DOI: 10.1016/j.jtbi.2010.09.042
  • Multiple outbreaks for the same pandemic: Local transportation and social distancing explain the different DOI: 10.3934/mbe.2011.8.21
  • Biophysical modeling of excitability and membrane integration at the single cell and network levels DOI: 10.1186/1471-2202-12-S1-P218
  • Differential contribution of A-type potassium currents in shaping neuronal responses to synaptic input DOI: 10.1186/1471-2202-12-S1-P147
  • Mitigating effects of vaccination on influenza outbreaks given constraints in stockpile size and daily administration capacity DOI: 10.1186/1471-2334-11-207twitter.com/brujonildo
  • The role of the large-conductance calcium-dependent potassium channel, BK/Slowpoke, in shaping motor neuron firing during rhythmic activity DOI: 10.1186/1471-2202-12-S1-P217
  • Differential contribution of voltage-dependent potassium currents to neuronal excitability DOI: 10.1186/1471-2202-11-S1-P159
  • Passive current transfer in wildtype and genetically modified Drosophila motoneuron dendrites DOI: 10.1186/1471-2202-10-S1-P346
  • Predicting changes in neuronal excitability type in response to genetic manipulations of K+-channels DOI: 10.1186/1471-2202-10-S1-P301
  • Analysis of spatial mobility in subjects from a Dengue endemic urban locality in Morelos State, Mexico, https://doi.org/10.1371/journal.pone.0172313

Marco's public data