Manuel Gentiluomo

Publications

• Common germline variants within the CDKN2A/2B region affect risk of pancreatic neuroendocrine tumors
• Functional single nucleotide polymorphisms within the cyclindependent kinase inhibitor 2A/2B region affect pancreatic cancer risk
• Genome-wide association study identifies an early onset pancreatic cancer risk locus
• In Pancreatic Adenocarcinoma Alpha-Synuclein Increases and Marks Peri-Neural Infiltration.
• Association between telomere length and mitochondrial copy number and cancer risk in humans: A meta-analysis on more than 300,000 individuals.
• Factors Associated With the Risk of Progression of Low-Risk Branch-Duct Intraductal Papillary Mucinous Neoplasms
• The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years' experience of association studies to understand the genetic architecture of pancreatic cancer
• Germline genetic variability in pancreatic cancer risk and prognosis
• Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients
• Association between a polymorphic variant in the CDKN2B-AS1/ANRIL gene and pancreatic cancer risk
• Common variability in oestrogen-related genes and pancreatic ductal adenocarcinoma risk in women
• A polymorphic variant in telomere maintenance is associated with worrisome features and high-risk stigmata development in IPMNs
• Genetic polymorphisms in inflammatory genes and pancreatic cancer risk: a two-phase study on more than 14 000 individuals
• Mitochondrial DNA Copy-Number Variation and Pancreatic Cancer Risk in the Prospective EPIC Cohort.
• Mendelian randomisation study of the effects of known and putative risk factors on pancreatic cancer.
• Genome-wide association study of mitochondrial copy number
• Role of OPRM1, clinical and anthropometric variants in neonatal pain reduction
• Polygenic and multifactorial scores for pancreatic ductal adenocarcinoma risk prediction.
• Telomere Length and Male Fertility
• Identification of Recessively Inherited Genetic Variants Potentially Linked to Pancreatic Cancer Risk
• Genome-wide scan of long noncoding RNA single nucleotide polymorphisms and pancreatic cancer susceptibility.
• Taste receptor polymorphisms and male infertility
• Polymorphic variants in Sweet and Umami taste receptor genes and birthweight.
• Lack of association of CD44-rs353630 and CHI3L2-rs684559 with pancreatic ductal adenocarcinoma survival.
• Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies.
• Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.
• Association of Genetic Variants Affecting microRNAs and Pancreatic Cancer Risk.
• TAS2R38 polymorphisms, Helicobacter pylori infection and susceptibility to gastric cancer and premalignant gastric lesions.
• Genetic polymorphisms involved in mitochondrial metabolism and pancreatic cancer risk.
• Genetically determined telomere length is associated with pancreatic neuroendocrine neoplasms onset
• Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma
• Genetic and non-genetic risk factors for early-onset pancreatic cancer
• Genetic variants in taste-related genes and risk of pancreatic cancer
• Long or short? Telomere length and pancreatic cancer and its precursor lesions, a narrative review
• Analysis of exposome and genetic variability suggests stress as a major contributor for development of pancreatic ductal adenocarcinoma
• Associations between pancreatic expression quantitative trait loci (eQTLs) and pancreatic ductal adenocarcinoma risk
• TUMOR VOLUME AND MICROSATELLITE INSTABILITY INVERSELY AFFECT EARLY PROGRESSION FREE SURVIVAL IN ADJUVANT SETTING OF PATIENTS WITH PANCREATIC DUCTAL ADENOCARCINOMA: LIGHTS AND SHADOWS OF MOLECULAR PATHOLOGY AND IMMUNOTHERAPY
• THE ROLE OF MOLECULAR PATHOLOGY AND IMMUNOTHERAPY IN ADJUVANT SETTING OF PANCREATIC DUCTAL ADENOCARCINOMA: TUMOR VOLUME AND MICROSATELLITE INSTABILITY INVERSELY AFFECT EARLY PROGRESSION FREE SURVIVAL
• Polymorphic variants within non-coding RNA and risk of pancreatic ductal adenocarcinoma
• Lights and shadows of molecular pathology and immunotherapy in adjuvant setting of patients with pancreatic ductal adenocarcinoma: Tumor volume and microsatellite instability inversely affect early progression free survival
• MICROSATELLITE INSTABILITY AND TUMOR VOLUME INVERSELY AFFECT EARLY PROGRESSION FREE SURVIVAL IN ADJUVANT SETTING OF PATIENTS WITH PANCREATIC DUCTAL ADENOCARCINOMA: LIGHTS AND SHADOWS OF MOLECULAR PATHOLOGY AND IMMUNOTHERAPY
• Exploring the Neandertal legacy of pancreatic ductal adenocarcinoma risk in Eurasians
• A scan of all coding region variants of the human genome, identifies 13q12.2-rs9579139 and 15q24.1-rs2277598 as novel risk loci for pancreatic ductal adenocarcinoma
• RNA-SCOPE TECHNOLOGY AND IMMUNOHISTOCHEMISTRY REVEAL LOW EXPRESSION OF MUC5AC IN METASTATIC PANCREATIC PATIENTS: EPIGENETIC PITFALLS OR A BETTER DISEASE STATUS?
• Epigenetic expression of MUC5AC in metastatic pancreatic patients using RNA-scope technology and immunohistochemistry
• Role of pancreatic ductal adenocarcinoma risk factors in intraductal papillary mucinous neoplasm progression
• Physical activity, sedentary behavior and pancreatic cancer risk: a Mendelian randomization study.
• Physical Activity, Sedentary Behavior, and Pancreatic Cancer Risk: A Mendelian Randomization Study
• Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk
• Association between a polymorphic variant in the CDKN2B-AS1/ANRIL gene and pancreatic cancer risk
• A pleiotropy scan to discover new susceptibility loci for pancreatic ductal adenocarcinoma
• Association of hypothyroidism with survival in pancreatic cancer: retrospective cohort study
• Potential association between PSCA rs2976395 functional variant and pancreatic cancer risk