Liam O'Mahony

Publications

• COST Action ‘ImpARAS’: what have we learnt to improve food allergy risk assessment. A summary of a 4 year networking consortium
• Dietary factors during pregnancy and atopic outcomes in childhood: a systematic review from the European Academy of Allergy and Clinical Immunology
• A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2
• Distribution of ACE2, CD147, CD26 and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors
• COVID‐19 pandemic: Practical considerations on the organization of an allergy clinic – an EAACI/ARIA Position Paper
• EAACI Biologicals Guidelines – Recommendations for severe asthma
• Efficacy and safety of treatment with omalizumab for chronic spontaneous urticaria ‐ a systematic review for the EAACI Biologicals Guidelines
• Efficacy and safety of dupilumab for moderate‐to‐severe atopic dermatitis: a systematic review for the EAACI Biologicals Guidelines
• Immunonutrition: the importance of a new European Academy of Allergy and Clinical Immunology working group addressing a significant burden and unmet need.
• EAACI Biologicals Guidelines-dupilumab for children and adults with moderate-to-severe atopic dermatitis.
• Inhibition of CpG methylation improves the barrier integrity of bronchial epithelial cells in asthma.
• Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma.
• Immunology of COVID-19: Mechanisms, clinical outcome, diagnostics, and perspectives-A report of the European Academy of Allergy and Clinical Immunology (EAACI).
• Use of biologicals in allergic and type-2 inflammatory diseases during the current COVID-19 pandemic: Position paper of Ärzteverband Deutscher Allergologen (AeDA)A, Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)B, Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)C, Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI)D, Luxemburgische Gesellschaft für Allergologie und Immunologie (LGAI)E, Österreichische Gesellschaft für Pneumologie (ÖGP)F in co-oper
• Reply to: Dietary diversity and childhood asthma - Dietary acid load, an additional nutritional variable to consider.
• ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020).
• Intranasal Bifidobacterium longum protects against viral-induced lung inflammation and injury in a murine model of lethal influenza infection.
• Long Term Disruption of Cytokine Signalling Networks are Evident in Patients that Required Hospitalisation for SARS‐CoV‐2 Infection
• The Maternal Diet Index in Pregnancy is associated with offspring allergic diseases: The Healthy Start Study
• Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing
• Mechanisms of microbe-immune system dialogue within the skin
• Vaccines and Allergic reactions: the past, the current COVID‐19 pandemic, and future perspectives
• Examining Associations Between Dietary Inflammatory Index in Pregnancy, Pro-inflammatory Cytokine and Chemokine Levels at Birth, and Offspring Asthma and/or Wheeze by Age 4 Years
• EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update)
• Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: A systematic review for the EAACI guidelines
• COVID‐19 pandemic and allergen immunotherapy – an EAACI survey
• A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2
• Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children
• Allergy‐related outcomes at 12 months in the CORAL birth cohort of Irish children born during the first COVID 19 lockdown
• Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic-Treated Mice
• Protocol for a systematic review of the diagnostic test accuracy of tests for IgE‐mediated food allergy
• Effects of non‐steroidal anti‐inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID‐19
• Metabolic rewiring and serotonin depletion in patients with postacute sequelae of COVID‐19
• Higher levels of bacterial DNA in serum associate with severe and fatal COVID‐19
• Microbiome-immune interactions and relationship to asthma severity
• Cellular and molecular mechanisms of allergic asthma
• Advanced glycation end product intake during pregnancy and offspring allergy outcomes: A Prospective cohort study
• Early-Life Respiratory Infections in Infants with Cow’s Milk Allergy: An Expert Opinion on the Available Evidence and Recommendations for Future Research
• Dangerous liaisons: Bacteria, antimicrobial therapies, and allergic diseases
• Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta‐analysis
• Mouse Models of Asthma: Characteristics, Limitations and Future Perspectives on Clinical Translation
• IL‐10 induces IgG4 production in NOD‐ scid Il2rγ null mice humanized by engraftment of peripheral blood mononuclear cells
• Spermidine and spermine exert protective effects within the lung
• EAACI Biologicals Guidelines—Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12–17 years old
• Fracture biomechanics influence local and systemic immune responses in a murine fracture-related infection model
• The impact of COVID‐19 lockdown on infants' coronavirus exposure and routine healthcare access in Ireland: The CORAL birth cohort study at 6 months.
• ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy
• Impact of Long COVID on health and quality of life [version 1; peer review: awaiting peer review]
• Environment‐Dependent Alterations of Immune Mediators in Urban and Rural South African Children with Atopic Dermatitis
• An Exopolysaccharide Produced by Bifidobacterium longum 35624® Inhibits Osteoclast Formation via a TLR2-Dependent Mechanism
• Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19
• EAACI Research and Outreach Committee: Improving standards and facilitating global collaboration through a Research Excellence Network
• Exposure of children to rural lifestyle factors associated with protection against allergies induces an anti-Neu5Gc antibody response
• Prioritizing research challenges and funding for allergy and asthma and the need for translational research—The European Strategic Forum on Allergic Diseases
• EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma
• Overview of in vivo and ex vivo endpoints in murine food allergy models: Suitable for evaluation of the sensitizing capacity of novel proteins?
• Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care
• Immune regulation by histamine and histamine-secreting bacteria
• EAACI position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis
• Anwendung von Biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen Covid-19-Pandemiea, b, c: Positionspapier des Ärzteverbands Deutscher Allergologen (AeDA)A, der Deutschen Gesellschaft für Allergologie und klinische Immunologie (DGAKI)B, der Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)C, der Österreichischen Gesellschaft für Allergologie und Immunologie (ÖGAI)D, der Luxemburgischen Gesellschaft für Allergologie und Immunologie (LGAI)E, der Österreichischen
• Microbiome and asthma.
• Erratum to: Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review.
• EPOS2020: development strategy and goals for the latest European Position Paper on Rhinosinusitis.
• A wide diversity of bacteria from the human gut produces and degrades biogenic amines.
• The frequency of CD4+ CD25+ FoxP3+ CD127‐cells in Bet v 1 contiguous overlapping peptide immunotherapy as a putative marker of efficacy
• Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients
• Recent developments and highlights in food allergy
• Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma
• Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement
• Handling of allergen immunotherapy in the COVID‐19 pandemic: An ARIA‐EAACI statement
• Short Chain Fatty Acids Modulate Mast Cell Activation
• Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma
• European Position Paper on Rhinosinusitis and Nasal Polyps 2020
• Efficacy and Safety of treatment with dupilumab for severe asthma
• Current perspective on eicosanoids in asthma and allergic diseases - EAACI Task Force consensus report, part I
• Use of biologicals in allergic and type 2 inflammatory diseases in the current COVID-19 pandemic,Anwendung von biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen COVID-19-Pandemie
• Exposure to nonmicrobial N-glycolylneuraminic acid protects farmers’ children against airway inflammation and colitis
• Mechanisms of food allergy
• Exopolysaccharide from Bifidobacterium longum subsp. Longum 35624™ modulates murine allergic airway responses
• Role of regulatory cells in oral tolerance
• Much ado about Biologicals: Highlights of the Master Class on Biologicals, Prague, 2018
• Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid
• Type 2 innate lymphoid cells disrupt bronchial epithelial barrier integrity by targeting tight junctions through IL-13 in asthmatic patients
• EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy
• Biology of the Microbiome 1: Interactions with the Host Immune Response
• AllergoOncology: Microbiota in allergy and cancer—A European Academy for Allergy and Clinical Immunology position paper
• AllergoOncology: Opposite outcomes of immune tolerance in allergy and cancer
• High levels of butyrate and propionate in early life are associated with protection against atopy
• Bacterial secretion of histamine within the gut influences immune responses within the lung
• Influence of fracture stability on staphylococcus epidermidis and staphylococcus aureus infection in a murine femoral fracture model
• Mechanisms underlying induction of allergic sensitization by Pru p 3
• Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis
• Pathogenic mechanisms and host interactions in Staphylococcus epidermidis device-related infection
• Recent developments and highlights in mechanisms of allergic diseases: Microbiome
• Histamine receptor 2 modifies iNKT cell activity within the inflamed lung
• Infection burden and immunological responses are equivalent for polymeric and metallic implant materials in vitro and in a murine model of fracture-related infection
• Emerging roles of innate lymphoid cells in inflammatory diseases: Clinical implications
• Altered fatty acid metabolism and reduced stearoyl-coenzyme a desaturase activity in asthma
• Microbiome and skin biology
• The importance of social networks—An ecological and evolutionary framework to explain the role of microbes in the aetiology of allergy and asthma
• Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High-risk Infants.
• Immune system in the intestine and mucosal inflammation.
• Davos declaration: allergy as a global problem.
• Safety and tolerance of dietary supplementation with a canine-derived probiotic (Bifidobacterium animalis strain AHC7) fed to growing dogs.
• Histamine receptors and inflammatory cells
• Allergen immunotherapy for IgE-mediated food allergy: Protocol for a systematic review
• Innate mechanisms can predict successful allergy immunotherapy
• Regulation of the immune response and inflammation by histamine and histamine receptors
• Davos declaration: Allergy as a global problem (Allergy: European Journal of Allergy and Clinical Immunology (2012) 67, (141-143))
• The surfaceassociated exopolysaccharide of Bifidobacterium longum 35624 plays an essential role in dampening host proinflammatory responses and repressing local TH17 responses
• The use of animal models to discover immunological mechanisms underpinning sensitization to food allergens
• Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: Challenges and opportunities toward precision medicine
• Histamine and gut mucosal immune regulation
• Consensus Communication on Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants
• Primary prevention of food allergy in children and adults: Systematic review
• Histamine receptor 2 modifies dendritic cell responses to microbial ligands
• Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases
• Genome analysis and characterisation of the exopolysaccharide produced by bifidobacterium longum subsp. Longum 35624™
• Salmonella adhesion, invasion and cellular immune responses are differentially affected by iron concentrations in a combined in vitro gut fermentation-cell model
• Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants
• Bifidobacterium infantis suppression of Peyer's patch MIP-1α and MIP-1β secretion during Salmonella infection correlates with increased local CD4+CD25+ T cell numbers
• Histamine regulation of innate and adaptive immunity
• Transport of Pru p 3 across gastrointestinal epithelium - an essential step towards the induction of food allergy?
• Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: Association with toll-like receptor 4 expression and plasma levels of interleukin 8
• EAACI Food Allergy and Anaphylaxis Guidelines. Primary prevention of food allergy
• Microbiome-Host Immune System Interactions
• The many routes of dendritic cells to ensure immune regulation
• Current challenges facing the assessment of the allergenic capacity of food allergens in animal models
• Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases
• Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut
• Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects
• Histamine-secreting microbes are increased in the gut of adult asthma patients
• Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice
• A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome
• Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: Potential role for myeloid and plasmacytoid dendritic cells
• The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology
• Microbiota and dietary interactions - An update to the hygiene hypothesis?
• Prebiotics, probiotics, synbiotics, and the immune system: Experimental data and clinical evidence
• Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease
• Intestinal dendritic cells
• Portrait of an immunoregulatory bifidobacterium
• Human dendritic cell DC-SIGN and TLR-2 mediate complementary immune regulatory activities in response to Lactobacillus rhamnosus JB-1
• Influence of microbiome and diet on immune responses in food allergy models
• Monitoring immune responses in a mouse model of fracture fixation with and without Staphylococcus aureus osteomyelitis
• Global allergy forum and second davos declaration 2013 allergy: Barriers to cure - Challenges and actions to be taken
• Bifidobacterium infantis 35624 protects against Salmonella-induced reductions in digestive enzyme activity in mice by attenuation of the host inflammatory response
• Histamine receptor 2 is a key influence in immune responses to intestinal histamine-secreting microbes
• Research needs in allergy: An EAACI position paper, in collaboration with EFA
• Host-microbiome interactions in health and disease
• Immunomodulation by Bifidobacterium infantis 35624 in the Murine Lamina Propria Requires Retinoic Acid-Dependent and Independent Mechanisms
• Probiotic lactobacillus salivarius strains
• Clinical benefits of probiotic canine-derived Bifidobacterium animalis strain AHC7 in dogs with acute idiopathic diarrhea.
• Probiotic bifidobacterium strains
• An exopolysaccharide
• Probiotic bifidobacterium strains
• Probiotic effects on inflammatory bowel disease.
• Probiotic bifidobacterium strains
• In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings.
• Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria
• Influence of the gut microbiota with ageing
• Probiotics in inflammatory bowel disease
• Section XII. Health Ingredients and Health Products Development for Preventing or Treating Human Diseases: Functional Foods and Gastrointestinal Disorders
• Immunology of the Small Intestine
• Safety and tolerance of dietary supplementation with a canine-derived probiotic (bifidobacterium animalis strain AHC7) fed to growing dogs
• Clinical benefits of probiotic canine-derived Bifidobacterium animalis strain AHC7 in dogs with acute idiopathic diarrhea
• Probiotic effects on inflammatory bowel disease
• In vitro selection criteria for probiotic bacteria of human origin: Correlation with in vivo findings
• Lactobacillus and Bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
• Novel immunotherapeutic approaches for allergy and asthma
• Mycobacterium avium subsp. Paratuberculosis (MAP) as a modifying factor in Crohn's disease
• Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease
• Salmonella typhimurium stimulation combined with tumour-derived heat shock proteins induces potent dendritic cell anti-tumour responses in a murine model
• Role of interleukin (IL-10) in probiotic-mediated immune modulation: An assessment in wild-type and IL-10 knock-out mice
• Portrait of a canine probiotic Bifidobacterium-From gut to gut
• Loss of vagal anti-inflammatory effect: In vivo visualization and adoptive transfer
• Effects of human recombinant growth hormone [rhGH) on inflammatory responses in patients undergoing abdominal aortic aneurysm repair
• Differential cytokine response from dendritic cells to commensal and pathogenic bacteria in different lymphoid compartments in humans
• Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius
• Irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease: A real association or reflection of occult inflammation
• Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome
• Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance
• Technical Advance: Function and efficacy of an α4-integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis
• Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis
• Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues
• Impact of administered bifidobacterium on murine host fatty acid composition
• Bifidobacterium animalis AHC7 protects against pathogen-induced NF-κB activation in vivo
• Probiotics: From myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials
• Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models
• Metabolic activity of probiotics-Oxalate degradation
• Mucosal cytokine imbalance in irritable bowel syndrome
• Mechanisms of adherence of a probiotic Lactobacillus strain during and after in vivo assessment in ulcerative colitis patients
• Involvement of T helper type 17 and regulatory T cell activity in Citrobacter rodentium invasion and inflammatory damage
• Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-κB activation
• Sulfate-reducing bacteria colonize pouches formed for ulcerative colitis but not for familial adenomatous polyposis
• Comparative and functional analysis of sortase-dependent proteins in the predicted secretome of Lactobacillus salivarius UCC118
• Protective effects of Lactobacillus reuteri and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve
• Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: Plasma cytokines as a potential biomarker?
• A randomised controlled trial of a probiotic Lactobacillus strain in healthy adults: Assessment of its delivery, transit and influence on microbial flora and enteric immunity
• Failure to define what constitutes a patient responder is a problem in the interpretation of the probiotic clinical trial evaluating the use of Bifidobacterium in irritable bowel syndrome [5] (multiple letters)
• Probiotic impact on microbial flora, inflammation and tumour development in IL-10 knockout mice
• Sylvester o'halloran surgical scientific meeting - Proceedings of meeting held 7th & 8th March 1997 in Charles parsons theatre, university of Limerick
• Quantitative intracellular cytokine measurement: Age-related changes in proinflammatory cytokine production
• Impact of Long COVID on health and quality of life [version 1; peer review: 1 approved]
• Impact of Long COVID on health and quality of life [version 1; peer review: 2 approved]
• Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
• Importance of examining atopic dermatitis disease mechanisms in African populations
• Environmental influences on childhood asthma—The effect of diet and microbiome on asthma
• Social communication skill attainment in babies born during the COVID-19 pandemic: a birth cohort study
• Comparing the Diagnostic Accuracy of Measures of Maternal Diet During Pregnancy for Offspring Allergy Outcomes: The Healthy Start Study
• Parenting a newborn baby during the COVID-19 pandemic: a qualitative survey
• Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity
• Role of dietary fiber in promoting immune health—An EAACI position paper
• Immunomodulation by foods and microbes: Unravelling the molecular tango
• The immune‐supportive diet in allergy management. A narrative review and proposal
• ARIA‐EAACI statement on severe allergic reactions to COVID‐19 vaccines – An EAACI‐ARIA Position Paper
• An update on recent developments and highlights in food allergy
• The impact of COVID-19 lockdown on infants’ coronavirus exposure and routine healthcare access in Ireland: the CORAL study at 6 months.
• Allergy related outcomes at 12 months in the CORAL birth cohort of Irish children born during the first COVID 19 lockdown.
• Atopic outcomes at 2 years in the CORAL cohort, born in COVID‐19 lockdown
• Role of dietary fiber in promoting immune health—An EAACI position paper
• IL‐10 induces IgG4 production in NOD‐ scid Il2rγ null mice humanized by engraftment of peripheral blood mononuclear cells
• Excessive inflammatory and metabolic responses to acute SARS-CoV-2 infection are associated with a distinct gut microbiota composition
• Rhinovirus-induced epithelial RIG-I inflammasome activation suppresses antiviral immunity and promotes inflammatory responses in virus-induced asthma exacerbations and COVID-19
• Disrupted epithelial permeability as a predictor of severe COVID-19 development
• Mapping the human genetic architecture of COVID-19
• Rural and urban exposures shape early life immune development in South African children with atopic dermatitis and nonallergic children
• Critical entry points-microbiome
• Probiotics: A role in therapy for inflammatory bowel disease
• Nutrition in chronic inflammatory conditions: Bypassing the mucosal block for micronutrients
• Systematic review of the association between short chain fatty acids and allergic diseases