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Gillian P. McHugo

Computational biology PhD researcher (Genomics and transcriptomics)

Ireland

Computational biology PhD researcher at University College Dublin studying integrative genomics of infectious diseases in cattle, focusing on trypanosomiasis in hybrid African cattle and bovine tuberculosis in Irish cattle.

Publications

  • Browett, S., McHugo, G., Richardson, I. W., Magee, D. A., Park, S. D. E., Fahey, A. G., Kearney, J. F., Correia, C. N., Randhawa, I. A. S., & MacHugh, D. E. (2018). Genomic characterisation of the indigenous Irish Kerry cattle breed. Frontiers in Genetics, 9, 51. doi:10.3389/fgene.2018.00051
  • McHugo, G. P., Browett, S., Randhawa, I. A. S., Howard, D. J., Mullen, M. P., Richardson, I. W., Park, S. D. E., Magee, D. A., Scraggs, E., Dover, M. J., Correia, C. N., Hanrahan, J. P., & MacHugh, D. E. (2019). A population genomics analysis of the native Irish Galway sheep breed. Frontiers in Genetics, 10, 927. doi:10.3389/fgene.2019.00927
  • McHugo, G. P., Dover, M. J., & MacHugh, D. E. (2019). Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics. BMC Biology, 17, 98. doi:10.1186/s12915-019-0724-7
  • Hall, T. J., Mullen, M. P., McHugo, G. P., Killick, K. E., Ring, S. C., Berry, D. P., Correia, C. N., Browne, J. A., Gordon, S. V., & MacHugh, D. E. (2021). Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria. BMC Genomics, 22, 343. doi:10.1186/s12864-021-07643-w
  • Ward, J. A., McHugo, G. P., Dover, M. J., Hall, T. J., Ng’ang’a, S. I., Sonstegard, T. S., Bradley, D. G., Frantz, L. A. F., Salter-Townshend, M., & MacHugh, D. E. (2022). Genome-wide local ancestry and evidence for mitonuclear coadaptation in African hybrid cattle populations. iScience, 25(7), 104672. doi:10.1016/j.isci.2022.104672
  • Correia, C. N., McHugo, G. P., Browne, J. A., McLoughlin, K. E., Nalpas, N. C., Magee, D. A., Whelan, A. O., Villarreal-Ramos, B., Vordermeier, H. M., Gormley, E., Gordon, S. V., & MacHugh, D. E. (2022). High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course. Tuberculosis, 136, 102235. doi:10.1016/j.tube.2022.102235
  • Bhat, S. A., Elnaggar, M., Hall, T. J., McHugo, G. P., Reid, C., MacHugh, D. E., & Meade, K. G. (2023). Preferential differential gene expression within the WC1.1+ γδ T cell compartment in cattle naturally infected with Mycobacterium bovis. Frontiers in Immunology, 14, 1265038. doi:10.3389/fimmu.2023.1265038
  • Hall, T. J., McHugo, G. P., Mullen, M. P., Ward, J. A., Killick, K. E., Browne, J. A., Gordon, S. V., & MacHugh, D. E. (2023). Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogens. Tuberculosis, 102453. doi:10.1016/j.tube.2023.102453.
  • Ward, J. A., Ng’ang’a, S. I., Randhawa, I. A. S., McHugo, G. P., O’Grady, J. F., Flórez, J. M., Browne, J. A., Pérez O’Brien, A. M., Landaeta-Hernández, A. J., Garcia, J. F., Sonstegard, T. S., Frantz, L. A. F., Salter-Townshend, M., & MacHugh, D. E. (2024). Genomic insights into the population history and adaptive traits of Latin American Criollo cattle. Royal Society Open Science, 11(3), 231388. doi:10.1098/rsos.231388.
  • Kelly, P. A., McHugo, G. P., Scaife, C., Peters, S., Stevenson, M. L., McKay, J. S., MacHugh, D. E., Saez, I. L., & Breathnach, R. (2024). Unveiling the role of endoplasmic reticulum stress pathways in canine demodicosis. Parasite Immunology, 46(4), e13033. doi:10.1111/pim.13033.

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