Frederik Holst

Broad Institute


  • High phospho-Stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition. DOI: 10.1158/1078-0432.CCR-12-3413
  • Prognostic relevance of AIB1 (NCoA3) amplification and overexpression in breast cancer. DOI: 10.1007/s10549-013-2406-4
  • Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. DOI: 10.1371/journal.pone.0054873
  • ESR1 Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. DOI: 10.1371/journal.pone.0084189
  • KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer. DOI: 10.1038/bjc.2012.477
  • Role of cyclin D1 amplification and expression in vulvar carcinomas. DOI: 10.1016/j.humpath.2011.11.014
  • Estrogen receptor alpha (ESR1) gene amplification status and clinical outcome in tamoxifen-treated postmenopausal patients with endocrine-responsive early breast cancer: An analysis of the prospective ABCSG-6 trial.
  • On the evidence for ESR1 amplification in breast cancer. DOI: 10.1038/nrc3093-c3
  • PPFIA1 and CCND1 are frequently coamplified in breast cancer. DOI: 10.1002/gcc.20713
  • Estrogen receptor gene amplification occurs rarely in ovarian cancer. DOI: 10.1038/modpathol.2008.130
  • Oestrogen receptor gene (ESR1) amplification is frequent in endometrial carcinoma and its precursor lesions. DOI: 10.1002/path.2405
  • Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. DOI: 10.1038/ng2006
  • Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. PMID: 11074789

Frederik's public data