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Alexander Lorenz

0000-0003-1925-3713

Senior Lecturer (Genetics not elsewhere classified)

Aberdeen

Since 2021: Senior Lecturer in Fungal Genetics; School of Medicine, Medical Sciences & Nutrition; University of Aberdeen, UK 2013-2021: Lecturer in Molecular Cell Biology; School of Medicine, Medical Sciences & Nutrition; University of Aberdeen, UK 2007-2013: Postdoctoral Research Associate at the Department of Biochemistry, University of Oxford, UK 2005-2007: Erwin Schrödinger-Fellow of the Austrian Science Fund (FWF) researching at the Department of Biochemistry, University of Oxford, UK 2003-2005: Postdoctoral Research Associate at the Department of Chromosome Biology, University of Vienna, Austria 1992-2003: Studying Botany and Genetics at the University of Vienna, Austria and at the University of Cologne, Germany

Publications

  • Origin of facultative heterochromatin in the endosperm of Gagea lutea (Liliaceae). DOI: 10.1007/BF01282922
  • Chromosome associations in budding yeast caused by integrated tandemly repeated transgenes. - Journal of Cell Science 115 (6): 1213-1220
  • Spatial organisation and behaviour of the parental chromosome sets in the nuclei of Saccharomyces cerevisiae x S. paradoxus hybrids. DOI: 10.1242/jcs.00066
  • Chromosome pairing does not contribute to nuclear architecture in vegetative yeast cells. DOI: 10.1128/EC.2.5.856-866.2003
  • S. pombe meiotic linear elements contain proteins related to synaptonemal complex components. DOI: 10.1242/jcs.01203
  • Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe. DOI: 10.1534/genetics.104.036301
  • Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion. DOI: 10.1091/mbc.E05-09-0839
  • Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe. DOI: 10.1007/s00412-006-0053-9
  • Crossover promotion and prevention. DOI: 10.1042/BST0340537
  • The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair. DOI: 10.1534/genetics.107.085696
  • The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair. DOI: 10.1016/j.molcel.2008.08.024
  • Analysis of Schizosaccharomyces pombe meiosis by nuclear spreading. DOI: 10.1007/978-1-60761-103-5_2
  • Fbh1 limits Rad51-dependent recombination at blocked replication forks. DOI: 10.1128/MCB.00471-09
  • The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant.DOI: 10.1093/nar/gkp1179
  • Roles of Hop1 and Mek1 in meiotic chromosome pairing and recombination partner choice in Schizosaccharomyces pombe. DOI: 10.1128/MCB.00919-09
  • A failure of meiotic chromosome segregation in a fbh1Δ mutant correlates with persistent Rad51-DNA associations. DOI: 10.1093/nar/gkq977
  • Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier. DOI: 10.1093/nar/gkr340
  • Mug20, a novel protein associated with linear elements in fission yeast meiosis. DOI: 10.1007/s00294-012-0369-3
  • The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability. DOI: 10.1101/gad.184663.111
  • The fission yeast FANCM ortholog directs non-crossover recombination during meiosis. DOI: 10.1126/science.1220111
  • How not to get cross(ed): A novel role for FANCM orthologs in meiotic recombination. DOI: 10.4161/cc.21844
  • Slx8 removes Pli1-dependent protein-SUMO conjugates including SUMOylated topoisomerase I to promote genome stability. DOI: 10.1371/journal.pone.0071960
  • Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination. DOI: 10.1093/nar/gku1219
  • New cassettes for single-step drug resistance and prototrophic marker switching in fission yeast. DOI: 10.1002/yea.3097
  • DNA double-strand break formation and repair in Tetrahymena meiosis. DOI: 10.1016/j.semcdb.2016.02.021
  • The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks. DOI: 10.1038/srep22837
  • Meiotic chromosome mobility in fission yeast is resistant to environmental stress. DOI: 10.1038/srep24222
  • Modulation of meiotic homologous recombination by DNA helicases. DOI: 10.1002/yea.3227
  • Single-stepmarker switching in Schizosaccharomyces pombe using a lithium acetate transformation protocol. DOI: 10.21769/BioProtoc.2075
  • Genetic interactions between the chromosome axis-associated protein Hop1 and homologous recombination determinants in Schizosaccharomyces pombe. DOI: 10.1007/s00294-018-0827-7
  • The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris. DOI: 10.1038/s41598-018-33199-z
  • Immediate visualization of recombination events and chromosome segregation defects in fission yeast meiosis. DOI: 10.1007/s00412-019-00691-y
  • Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates. DOI: 10.1007/s00294-019-00976-w
  • ABC transporter genes show upregulated expression in drug resistant clinical isolates of Candida auris: a genome-wide characterization of ATP-Binding Cassette (ABC) transporter genes. DOI: 10.3389/fmicb.2019.01445
  • DNA sequence differences are determinants of meiotic recombination outcome. DOI: 10.1038/s41598-019-52907-x
  • Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint. DOI: 10.1128/mSphere.00151-20
  • Intragenic meiotic recombination in Schizosaccharomyces pombe is sensitive to environmental temperature changes. DOI: 10.1007/s10577-020-09632-3
  • Candida auris: The path of yeast resistance. DOI: 10.32907/RO-113-138141
  • Catalase T‐deficient fission yeast meiocytes show resistance to ionizing radiation. DOI: 10.3390/antiox9090881
  • Is Candida auris sexual? DOI: 10.1371/journal.ppat.1009094
  • What do we know about the biology of the emerging fungal pathogen of humans Candida auris? DOI: 10.1016/j.micres.2020.126621
  • The curious case of nonrepetitive centromeric DNA sequences in Candida auris and related species. DOI: 10.1128/mBio.01476-21
  • New tools for the new bug Candida auris. DOI: 10.1016/j.tim.2022.01.010
  • Gene conversion: a non-Mendelian process integral to meiotic recombination. DOI: 10.1038/s41437-022-00523-3
  • Mendel’s laws of heredity on his 200th birthday: What have we learned by considering exceptions? DOI: 10.1038/s41437-022-00552-y
  • Genetic transformation of Candida auris via homology-directed repair using a standard lithium acetate protocol. DOI: 10.1007/978-1-0716-2417-3_8
  • Labelling of Candida auris cell walls to examine levels of PAMP exposure by flow cytometry and fluorescence microscopy. DOI: 10.1007/978-1-0716-2417-3_14
  • [ed] Candida auris: Methods and Protocols. DOI: 10.1007/978-1-0716-2417-3

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Co-workers & collaborators

Matthew Whitby

Matthew Whitby

Alexander Lorenz's public data