Alexander Lancaster

Publications

• COSMOS: Python library for massively parallel workflows. PMID: 24982428
• PLAAC: a web and command-line application to identify proteins with Prion-Like Amino Acid Composition. DOI: 10.1093/bioinformatics/btu310
• Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity (vol 7, pg 1520, 2012) DOI: 10.1021/cb5000339
• Multi-tissue transcriptomics of the black widow spider reveals expansions, co-options, and functional processes of the silk gland gene toolkit. PMID: 24916340
• Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B. DOI: 10.1371/journal.pbio.1001692
• Yeast Reveal a "Druggable" Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons. DOI: 10.1126/science.1245321
• Fresh Insights from RNA-Seq Analysis into Black Widow Spider Venom Composition and Evolution ISSN: 1540-7063
• Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion ISSN: 0092-8674
• Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity DOI: 10.1021/cb300235m
• Prions are a common mechanism for phenotypic inheritance in wild yeasts ISSN: 0028-0836
• A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statement. DOI: 10.1111/j.1399-0039.2011.01777.x
• The spontaneous appearance rate of the yeast prion [PSI+] and its implications for the evolution of the evolvability properties of the [PSI+] system. DOI: 10.1534/genetics.109.110213
• A hierarchical analysis of selection at the HLA-DPB1 locus reveals the action of balancing selection operating on DP serological categories ISSN: 0001-2815
• Toward a community standard for immunogenetics data reporting and analysis ISSN: 0001-2815
• HLA-A, -B, -C, and-DRB1 allele and haplotype frequencies distinguish Eastern European Americans from the general European American population ISSN: 0001-2815
• IDAWG - THE IMMUNOGENOMIC DATA-ANALYSIS WORKING GROUP. ISSN: 0198-8859
• THE EVOLUTION OF REVERSIBLE SWITCHES IN THE PRESENCE OF IRREVERSIBLE MIMICS ISSN: 0014-3820
• Balancing selection and heterogeneity across the classical human leukocyte antigen loci: A meta-analytic review of 497 population studies ISSN: 0198-8859
• GLOBAL PATTERNS OF POLYMORPHISM AND SELECTION AT THE CLASSICAL HLA LOCI: A META-ANALYSIS OF 497 POPULATION STUDIES ISSN: 0198-8859
• Selection at the amino acid level for HLA class I and class II loci ISSN: 0001-2815
• PyPop update--a software pipeline for large-scale multilocus population genomics. DOI: 10.1111/j.1399-0039.2006.00769.x
• 14th International HLA and Immunogenetics Workshop: Report of progress in methodology, data collection, and analyses ISSN: 0001-2815
• HLA Haplotypes in Singapore: A Study of Mothers and Their Cord Blood Units ISSN: 0198-8859
• HLA-A, -B, -C, -DRB1 allele and haplotype frequencies in an African American population ISSN: 0001-2815
• PyPop update - a software pipeline for large-scale multilocus population genomics ISSN: 0001-2815
• Population genetic analyses of the 13th IHW anthropology data ISSN: 0198-8859
• Signatures of demographic history and natural selection in the human MHC - a comparative study ISSN: 0001-2815
• Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci ISSN: 0001-2815
• High resolution HLA-DRB1 identification of a caucasian population ISSN: 0198-8859
• PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data. ISSN: 2335-6936
• Therapeutic engineering: Models of individual variability in drug systems ISSN: 1-880843-37-4
• Science and technology consortia in U.S. biomedical research: A paradigm shift in response to unsustainable academic growth. PMID: 25387399
• Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism DOI: 10.1016/j.cell.2014.07.025
• An Evolutionarily Conserved Prion-like Element Converts Wild Fungi from Metabolic Specialists to Generalists DOI: 10.1016/j.cell.2014.07.024