Figure_9.tif (548.4 kB)
TLR4−/− mice do not develop an antibody response to SLPs following infection.
figure
posted on 2011-06-30, 00:22 authored by Anthony Ryan, Mark Lynch, Sinead M. Smith, Sylvie Amu, Hendrik J. Nel, Claire E. McCoy, Jennifer K. Dowling, Eve Draper, Vincent O'Reilly, Ciara McCarthy, Julie O'Brien, Déirdre Ní Eidhin, Mary J. O'Connell, Brian Keogh, Charles O. Morton, Thomas R. Rogers, Padraic G. Fallon, Luke A. O'Neill, Dermot Kelleher, Christine E. LoscherMice were pre-treated with antibiotics and infected with C. difficile (see materials and methods). Serum was collected on day 3 of infection and the levels of anti-SLP IgG were measured using ELISA. Results are shown as absorbance values for wildtype versus TLR4−/− mice on day 3 of infection at a range of dilutions of serum. Results are expressed as mean ± SEM.
