pbio.3002546.s003.pptx (72.87 kB)
Model for the function of ZepA.
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posted on 2024-03-11, 17:42 authored by Cristina Sarasa-Buisan, Jesús A. G. Ochoa de Alda, Cristina Velázquez-Suárez, Miguel Ángel Rubio, Guadalupe Gómez-Baena, María F. Fillat, Ignacio LuqueThe picture shows a theoretical model based on results presented in this manuscript of zinc acquisition mediated by ZepA in Anabaena. Zinc atoms are depicted as yellow dots. OM stands for outer membrane and PM for plasma membrane. Cylinders on the outer membrane represent Zur-regulated TBDTs All3242 and All4028-4029. Dashed arrows indicate steps that will need to be further investigated.
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phylogenetic analysis suggestsexperimental evidence showeddistant bacterial lineagescomparative proteomics conductedpotential zinc limitationdiv >< pzur proteinzur mayzur zinc acquisitionzepa representszepa homologszepa wild typetuned responsesresults showputative functionprimordial systemmutant comparedkey playergenomic contextfur familyfirst regulatorsdeveloped fineanabaena abundant proteins
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