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Additional file 3: of Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome

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posted on 2019-07-19, 04:17 authored by Patrick Hargreaves, Douglas Daoudlarian, Michel Theron, Fabrice Kolb, Marianne Manchester Young, Bernhard Reis, Andre Tiaden, Bettina Bannert, Diego Kyburz, Tobias Manigold
Figure S3. Stability of CatS activity in tear fluid upon storage at − 80 °C. Specifically, tear fluid was stored at − 80 °C on the day of sample acquisition for 7–8 days until the first measurement. After testing, they were re-stored at − 80 °C over a period of 6 (HC1 and pSS2) and 8 (pSS1) weeks, respectively, until the second measurement. As indicated, CatS activity was stable, with a trend towards higher levels in the second test, but below 20% of variation, which is considered acceptable for bioassays. (PPTX 67 kb)

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