In the publication "Genome Sequence of Two Novel Virulent Clinical Strains of Burkholderia pseudomallei Isolated from Acute Melioidosis Cases Imported to Israel from India and Thailand" to which the online resource pertains, we report the genomes of two novel clinical isolates (MWH2021 and MST2022) of Burkholderia pseudomallei identified in two distinct acute cases of melioidosis diagnosed in two individuals arriving to Israel from India and Thailand, respectively. The publication includes preliminary genetic analysis of the genomes determining their phylogenetic classification in rapport to the genomes of other Burkholderia pseudomallei strains documented in the NCBI database. Inspection of the genetic data established the presence or absence of loci encoding for several important virulence determinants involved in the molecular pathogenesis of melioidosis. Virulence analysis in murine models of acute or latent melioidosis established that both strains belong to the highly virulent class of Burkholderia pseudomalleii.
