Supplementary Videos
Supplementary Video 1 6D dynamic tractography demonstrating early CCSR-based neural propagations from the temporal lobe sites.
Each animation movie demonstrates the trajectories of rapid neural propagations elicited by single-pulse electrical stimulation at temporal lobe sites supporting a specific linguistic stage. It shows group-level effective connectivity data derived from 27 patients who underwent diffusion-weighted imaging preoperatively. To optimize the visibility, each movie delineates the effective connectivity pathways satisfying the following criteria: [a] stimulus sites showed naming-related high-gamma augmentation during a specific PCA-based linguistic stage, [b] the interaction of high-gamma activity was above 200, and [c] a given streamline was associated with a significant early cortico-cortical spectral response (CCSR). The streamline color reflects the interaction of high-gamma activity at temporal and extra-temporal lobe sites during a given linguistic stage. Thus, red streamlines reflect high-gamma co-augmentation at both stimulus and recording sites, whereas blue ones indicate high-gamma augmentation at the stimulus sites but suppression at the recording sites. The size of each white dot reflects the strength of effective connectivity rated by early CCSR. The location of each white dot indicates the location of stimulation-induced neural propagation estimated by the propagation velocity. A.U. = arbitrary unit; HGA= high-gamma activity; PC = principal component; PCA = principal component analysis
Supplementary Video 2 6D dynamic tractography demonstrating early CCSR-based neural propagations from the extratemporal lobe sites.
Each animation movie demonstrates the trajectories of rapid neural propagations elicited by single-pulse electrical stimulation at extratemporal lobe sites supporting a specific linguistic stage. It shows group-level effective connectivity data derived from 27 patients who underwent diffusion-weighted imaging preoperatively. To optimize the visibility, each movie delineates the effective connectivity pathways satisfying the following criteria: [a] stimulus sites showed naming-related high-gamma augmentation during a specific PCA-based linguistic stage, [b] the interaction of high-gamma activity was above 200, and [c] a given streamline was associated with a significant early cortico-cortical spectral response (CCSR). The streamline color reflects the interaction of high-gamma activity at temporal and extra-temporal lobe sites during a given linguistic stage. Thus, red streamlines reflect high-gamma co-augmentation at both stimulus and recording sites, whereas blue ones indicate high-gamma augmentation at the stimulus sites but suppression at the recording sites. The size of each white dot reflects the strength of effective connectivity rated by early CCSR. The location of each white dot indicates the location of stimulation-induced neural propagation estimated by the propagation velocity. A.U. = arbitrary unit; HGA: high-gamma activity; PC = principal component; PCA = principal component analysis
