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posted on 2022-04-04, 17:36 authored by Emmanuel Gallaud, Laurent Richard-Parpaillon, Laetitia Bataillé, Aude Pascal, Mathieu Métivier, Vincent Archambault, Régis Giet

Polo variants expressed in polo mutant NSCs larval NSCs of the indicated genotypes (from left to right: wild-type, polo mutant, polo mutant expressing PoloWT:: GFP and polo mutant expressing PoloT182D::GFP) expressing mCherry::Tubulin under the control of Insc-Gal4. Microtubule marker and Polo variants are shown in magenta and green respectively. PoloWT is able to restore a normal mitotic timing in polo mutant while PoloT182D decreases the mitotic delay by more than half. Scale bar: 5 μm. Time is min:s. « 00:00 » corresponds to NEBD.