pcbi.1009476.s004.avi (904.57 kB)
Break-up of spiral waves, induced by global periodic sub-threshold electrical stimulation, at frequency 1.0 Hz, with a pulse length of 20 ms.
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posted on 2021-10-08, 17:32 authored by Rupamanjari Majumder, Sayedeh Hussaini, Vladimir S. Zykov, Stefan Luther, Eberhard BodenschatzThe filled red circle appearing at the top right corner (of select frames) of the video indicates the application of the stimulus in these frames.
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threshold illumination régimespatially extended mediumlesser studied sublethal rhythm disordershuman atrial tissuecardiac arrhythmia researchnonlinear wave propagationdiv >< pcardiac arrhythmias requireswave break initiationcardiac tissuecardiac rhythmwave breakcalled arrhythmiaswave profilewave breakswaveback interactionsudden deathsilico restitution characteristicspotentially lifenew mechanismmechanism involvesmain causesindustrialized worldimportant questionsimportant contributionidentifies scenariosheterogeneous recoverygentle slopesexcitable windowsenergy perturbationsdetailed understandingconduction blockscommonly referredbreaks evolve
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