mRNAs differentially expressed in the spinal cord lesion region in rats with SCI.

After contusion, total RNA was extracted from the lesion region of rats with SCI or from healthy non-injured controls (Control) 1 day or 7 days (1d and 7d, respectively) and treated with saline vehicle (S) or A-HOA (HOA). mRNA was quantified by microarray analysis. ANOVA following the false discovery rate (FDR) P value correction used to detect significant changes. The figure shows hierarchical clustering in the 5 experimental groups showing the expression levels from green (low) to red (high). Expression levels using the color code indicated at the bottom of the graph is shown for all four animals from each experimental group.