ppat.1012050.s006.pdf (155.97 kB)
13C-lactate metabolic flux analysis results.
journal contribution
posted on 2024-02-29, 18:55 authored by Sydney Stanley, Xin Wang, Qingyun Liu, Young Yon Kwon, Abigail M. Frey, Nathan D. Hicks, Andrew J. Vickers, Sheng Hui, Sarah M. FortuneThe error bars represent the standard deviation of three technical replicates. Blue indicates labeled carbon ions, grey represents total carbon ions.
(PDF)
History
Usage metrics
Categories
Keywords
providing experimental evidencediv >< pcentral carbon metabolism1 virulence systemmycobacterium tuberculosis discernible growth defectdependent antibiotic susceptibilitymutations functionally increasehuman host environmentglobal clinical isolateslactate dehydrogenase revealsassessing mtb genes13 supclinical isolatesvivo mtb growthlactate dehydrogenaseintracellular environmenthost pressuregenes involveddependent lvariation acrosstranscriptionally sensitivesugar phosphatesstrongest targetsstepwise natureselective advantagesalient featurerobust incorporationprovides contextpressures facingpoorly characterizedpleiotropic effectsmycobacterial cellmultifunctional rolemtb genomelldd2 lactate accumulationfunctional reporterdetoxification benefitdeleterious buildupdefining mutationsdata illustratebacterial determinantsbacterial adaptionancestral lineage
Licence
Exports
RefWorksRefWorks
BibTeXBibTeX
Ref. managerRef. manager
EndnoteEndnote
DataCiteDataCite
NLMNLM
DCDC