pone.0249110.s005.pdf (198.58 kB)
Western blot showing expression of MCT1 fusion constructs with BSG Ig-I carrying mutations of charged residues in the negative and positive patches.
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posted on 2021-03-26, 17:30 authored by Anna-Lena Köpnick, Annika Jansen, Katharina Geistlinger, Nathan Hugo Epalle, Eric BeitzGlu → Gln (Glu114,118,120,168,172), Lys/Arg → Ala (Lys108,111,127 plus Arg201,203) or as indicated.
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basigin Ig-I domainmonocarboxylate transporter familybasigin Ig-I domain drives lactate ...Basigin drives intracellular accumu...extracellular Ig-I domainprotoncharge-affecting Ig-I mutantsextracellular MCT entry sitebivalent harvesting antenna functio...transmembrane lsubstrate anions Transmembrane tran...
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