Visible-Light-Induced Cascade Cyclization of 1‑Acryloyl-2-cyanoindole: Access of Difluoroalkylated Pyrrolo[1,2‑a]indolediones

An effective method for accessing diverse difluoroalkylated pyrrolo[1,2-a]indolediones via visible-light-induced PhI(OAc)₂-promoted cascade difluoroalkylation/cyclization reaction under mild conditions has been established. This method is noteworthy for its use of DMSO–H₂O as a green medium at room temperature and avoidance of photocatalysts. The reactions are straightforward to execute and convenient to expand on, provide good to excellent yields, and have good functional group tolerance.