ppat.1010032.s007.docx (32.28 kB)
Virus-host fusion transcripts identified by Nanopore analysis of HPV18 genome containing HFKs.
journal contribution
posted on 2021-11-04, 17:51 authored by Jack Ferguson, Karen Campos-León, Ieisha Pentland, Joanne D. Stockton, Thomas Günther, Andrew D. Beggs, Adam Grundhoff, Sally Roberts, Boris Noyvert, Joanna L. ParishShowing the nearest annotated human gene, coordinates of identified transcripts mapped to the human (Hg19) and HPV genomes and the number of reads detected.
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viral transcript speciesubiquitous host proteinstabilise chromatin loopsmaintain epigenetic boundariesl1 protein expressiondependent chromatin loopingread nanopore rnahpv life cyclebinding deficient genomecharacterise ctcf functionhpv transcription controlnanopore analysiscellular transcriptionctcf bindingbinding factorxlink ">utilised directundifferentiated keratinocytestranscripts producedsites sd3165regulate splicingprovides informationpreviously demonstratednucleotide 3434length transcriptskey regulatorhuman papillomavirusfindings demonstrateessential regulatorefficient e1data showctcf bindsctcf ),containing cellsalternative exons
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